DNA is the molecule chosen by nature to store the information required to build organisms.
These organisms in turn serve to replicate that information. It was initially thought that DNA …

Nucleotide excision repair (NER) has allowed bacteria to flourish in many different niches
around the globe that inflict harsh environmental damage to their genetic material. NER is …

Chloroplasts produce singlet oxygen (1O2), which causes changes in nuclear gene
expression through plastid-to-nucleus retrograde signaling to increase plant fitness …

Helicases must unwind DNA at the right place and time to maintain genomic integrity or
gene expression. Biologically critical XPB and XPD helicases are key members of the …

How DNA repair proteins sort through a genome for damage is one of the fundamental
unanswered questions in this field. To address this problem, we uniquely labeled bacterial …

Bacillus cereus is a food-borne pathogen that causes diarrheal disease in humans. After
ingestion, B. cereus experiences in the human gastro-intestinal tract abiotic physical …

The chloroplast is a critical battleground in the arms race between plants and pathogens.
Among microbe-secreted mycotoxins, tenuazonic acid (TeA), produced by the genus …

DNA damage recognition represents a long-standing problem in the field of protein–DNA
interactions. This article reviews our current knowledge of how damage recognition is …

DNA-damage recognition in the nucleotide excision repair (NER) cascade is a complex
process, operating on a wide variety of damages. UvrB is the central component in …

Chloroplasts are recognized as environmental sensors, capable of translating
environmental fluctuations into diverse signals to communicate with the nucleus. Among the …