Pathogenicity and virulence of Streptococcus pneumoniae: Cutting to the chase on proteases
ME Marquart - Virulence, 2021 - Taylor & Francis
Bacterial proteases and peptidases are integral to cell physiology and stability, and their
necessity in Streptococcus pneumoniae is no exception. Protein cleavage and processing …
necessity in Streptococcus pneumoniae is no exception. Protein cleavage and processing …
The oxidative stress response of Streptococcus pneumoniae: its contribution to both extracellular and intracellular survival
M Hernandez-Morfa, NB Olivero, VE Zappia… - Frontiers in …, 2023 - frontiersin.org
Streptococcus pneumoniae is a gram-positive, aerotolerant bacterium that naturally
colonizes the human nasopharynx, but also causes invasive infections and is a major cause …
colonizes the human nasopharynx, but also causes invasive infections and is a major cause …
An in vivo atlas of host–pathogen transcriptomes during Streptococcus pneumoniae colonization and disease
Streptococcus pneumoniae (Spn) colonizes the nasopharynx and can cause pneumonia.
From the lungs it spreads to the bloodstream and causes organ damage. We characterized …
From the lungs it spreads to the bloodstream and causes organ damage. We characterized …
[HTML][HTML] The role of streptococcal cell-envelope proteases in bacterial evasion of the innate immune system
Bacteria possess the ability to evolve varied and ingenious strategies to outwit the host
immune system, instigating an evolutionary arms race. Proteases are amongst the many …
immune system, instigating an evolutionary arms race. Proteases are amongst the many …
In vivo proteomics identifies the competence regulon and AliB oligopeptide transporter as pathogenic factors in pneumococcal meningitis
F Schmidt, N Kakar, TC Meyer, M Depke… - PLoS …, 2019 - journals.plos.org
Streptococcus pneumoniae (pneumococci) is a leading cause of severe bacterial meningitis
in many countries worldwide. To characterize the repertoire of fitness and virulence factors …
in many countries worldwide. To characterize the repertoire of fitness and virulence factors …
Dual RNA-seq in Streptococcus pneumoniae infection reveals compartmentalized neutrophil responses in lung and pleural space
ND Ritchie, TJ Evans - Msystems, 2019 - Am Soc Microbiol
Streptococcus pneumoniae is the dominant cause of community-acquired pneumonia
worldwide. Invasion of the pleural space is common and results in increased mortality. We …
worldwide. Invasion of the pleural space is common and results in increased mortality. We …
Chemical warfare at the microorganismal level: a closer look at the superoxide dismutase enzymes of pathogens
SS Schatzman, VC Culotta - ACS infectious diseases, 2018 - ACS Publications
Superoxide anion radical is generated as a natural byproduct of aerobic metabolism but is
also produced as part of the oxidative burst of the innate immune response design to kill …
also produced as part of the oxidative burst of the innate immune response design to kill …
Intranasal vaccination with lipoproteins confers protection against pneumococcal colonisation
F Voß, TP Kohler, T Meyer, MR Abdullah… - Frontiers in …, 2018 - frontiersin.org
Streptococcus pneumoniae is endowed with a variety of surface-exposed proteins
representing putative vaccine candidates. Lipoproteins are covalently anchored to the cell …
representing putative vaccine candidates. Lipoproteins are covalently anchored to the cell …
Advances in understanding the specificity function of transporters by machine learning
Understanding the underlying molecular mechanism of transporter activity is one of the
major discussions in structural biology. A transporter can exclusively transport one ion …
major discussions in structural biology. A transporter can exclusively transport one ion …
Identifying genes associated with invasive disease in S. pneumoniae by applying a machine learning approach to whole genome sequence ty** data
Streptococcus pneumoniae, a normal commensal of the upper respiratory tract, is a major
public health concern, responsible for substantial global morbidity and mortality due to …
public health concern, responsible for substantial global morbidity and mortality due to …