Malaria poses a severe public health risk and a significant economic burden in disease-
endemic countries. One of the most severe issues in malaria control is the development of …

Chalcones represent key structural motif in the plethora of biologically active molecules
including synthetic and natural products. Synthetic manipulations of chalcones or their …

Chalcones (1, 3-diaryl-2-propen-1-ones) and their heterocyclic analogues, belong to the
flavonoid family, which possess a number of interesting biological properties such as …

Chalcones and their analogs have been an area of great interest in recent years. Numerous
research papers have been published, and chalcones continue to show promise for new …

Malaria remains a serious worldwide health danger and massive economic trouble to
disease-endemic nations. Presently, 250 million of malarial cases are expected worldwide …

Pyrazolines remain privileged heterocycles in drug discovery. 2-Pyrazoline scaffold has
been proven as a ubiquitous motif which is present in a number of pharmacologically …

In recent years, widespread outbreak of numerous infectious diseases across the globe has
created havoc among the population. Particularly, the inhabitants of tropical and sub-tropical …

A new series of chalcone–coumarin derivatives (9–19) linked by the 1, 2, 3-triazole ring
were synthesized through the azide/alkyne dipolar cycloaddition. Hybrid molecules were …

Chalcones belong to the flavonoid family which constitutes one of the major classes of
naturally occurring oxygen heterocyclic compounds. The α, β-unsaturated carbonyl system …

Naturally and synthetically derived hybrid molecules are an attractive source for therapeutic
agent development due to their dual or multiple modes of action and other advantages …