Plant‐derived extracellular vesicles: Recent advancements and current challenges on their use for biomedical applications

MQ Lian, WH Chng, J Liang, HQ Yeo… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) represent a diverse class of lipid bilayer membrane vesicles
released by both animal and plant cells. These ubiquitous vesicles are involved in …

Technology insight: Plant-derived vesicles—How far from the clinical biotherapeutics and therapeutic drug carriers?

M Cong, S Tan, S Li, L Gao, L Huang, HG Zhang… - Advanced drug delivery …, 2022 - Elsevier
Within the past decades, extracellular vesicles (EVs) have emerged as important mediators
of intercellular communication in both prokaryotes and higher eukaryotes to regulate a …

Plant-derived extracellular vesicles and their exciting potential as the future of next-generation drug delivery

FA Alzahrani, MI Khan, N Kameli, E Alsahafi, YM Riza - Biomolecules, 2023 - mdpi.com
Plant cells release tiny membranous vesicles called extracellular vesicles (EVs), which are
rich in lipids, proteins, nucleic acids, and pharmacologically active compounds. These plant …

Plant‐derived exosome‐like nanoparticles: A concise review on its extraction methods, content, bioactivities, and potential as functional food ingredient

S Suharta, A Barlian, AC Hidajah… - Journal of food …, 2021 - Wiley Online Library
Plant‐derived exosome‐like nanoparticles (PDENs) are small vesicles released by
multivesicular bodies mainly to communicate between cells and regulate immunity against …

Plant-derived extracellular vesicles as oral drug delivery carriers

Z Fang, K Liu - Journal of Controlled Release, 2022 - Elsevier
Oral administration is one of the most convenient and widely utilized methods of drug
administration. However, many drugs were difficult to be administered orally due to their …

Edible plant-derived exosomal microRNAs: Exploiting a cross-kingdom regulatory mechanism for targeting SARS-CoV-2

SP Kalarikkal, GM Sundaram - Toxicology and applied pharmacology, 2021 - Elsevier
Background The current COVID-19 pandemic is caused by SARS-CoV-2 which belongs to
coronaviridae family. Despite the global prevalence, there are currently no vaccines or …

[HTML][HTML] Plant-derived nanovesicles: current understanding and applications for cancer therapy

NP Ly, HS Han, M Kim, JH Park, KY Choi - Bioactive Materials, 2023 - Elsevier
Plant-derived vesicles (PDVs) are membranous structures that originate from plant cells and
are responsible for multiple physiological and pathological functions. In the last decade …

Alternative biological sources for extracellular vesicles production and purification strategies for process scale-up

S Giancaterino, C Boi - Biotechnology Advances, 2023 - Elsevier
Extracellular vesicles (EVs) are phospholipidic bi-layer enclosed nanoparticles secreted
naturally by all cell types. They are attracting increasing attention in the fields of …

Focusing on future applications and current challenges of plant derived extracellular vesicles

Y Wang, J Wang, J Ma, Y Zhou, R Lu - Pharmaceuticals, 2022 - mdpi.com
Plant derived extracellular vesicles (EVs) are nano-sized membranous vesicles released by
plant cells, which contain lipids, proteins, nucleic acids and specific pharmacologically …

Plant-derived nano and microvesicles for human health and therapeutic potential in nanomedicine

M Alfieri, A Leone, A Ambrosone - Pharmaceutics, 2021 - mdpi.com
Plants produce different types of nano and micro-sized vesicles. Observed for the first time in
the 60s, plant nano and microvesicles (PDVs) and their biological role have been …