Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …

Macrophages play an important role in cancer development and metastasis.
Proinflammatory M1 macrophages can phagocytose tumor cells, while anti‐inflammatory M2 …

One of the defining characteristics of a pre-metastatic niche, a fundamental requirement for
primary tumor metastasis, is infiltration of immunosuppressive macrophages. How these …

Background Liver metastasis (LM) is a major obstacle to the prognosis of gastric cancer
(GC) patients, but the molecular mechanism underlying gastric cancer liver metastasis (GC …

This study investigated the effects of water-soluble polysaccharide extracted from the
sporoderm-removed spores of Ganoderma lucidum (GLP) against AOM/DSS-induced …

Dysregulated inflammatory responses play a pivotal role in the initiation, development, and
progression of tumors, as demonstrated by the association between ulcerative colitis and the …

Macrophages play a key role in defending against foreign pathogens, healing wounds, and
regulating tissue homeostasis. Driving this versatility is their phenotypic plasticity, which …

Aim: To elucidate dynamics and functions in colonic macrophage subsets, and their
regulation by Bifidobacterium breve (B. breve) and its associated metabolites in the initiation …

Heterotopic ossification (HO) is the formation of extraskeletal bone in non-osseous tissues. It
is caused by an injury that stimulates abnormal tissue healing and regeneration, and …

Gut microbiota is a complex microbial community with the ability of maintaining intestinal
health. Intestinal homeostasis largely depends on the mucosal immune system to defense …