Anaemia and malaria

NJ White - Malaria journal, 2018 - Springer
Malaria is a major cause of anaemia in tropical areas. Malaria infection causes haemolysis
of infected and uninfected erythrocytes and bone marrow dyserythropoiesis which …

Malaria chemoprevention and drug resistance: a review of the literature and policy implications

CV Plowe - Malaria Journal, 2022 - Springer
Chemoprevention strategies reduce malaria disease and death, but the efficacy of anti-
malarial drugs used for chemoprevention is perennially threatened by drug resistance. This …

New developments in anti-malarial target candidate and product profiles

JN Burrows, S Duparc, WE Gutteridge… - Malaria journal, 2017 - Springer
A decade of discovery and development of new anti-malarial medicines has led to a
renewed focus on malaria elimination and eradication. Changes in the way new anti …

Sterile protection against human malaria by chemoattenuated PfSPZ vaccine

B Mordmüller, G Surat, H Lagler, S Chakravarty… - Nature, 2017 - nature.com
A highly protective malaria vaccine would greatly facilitate the prevention and elimination of
malaria and containment of drug-resistant parasites. A high level (more than 90%) of …

Malaria medicines: a glass half full?

TNC Wells, RH Van Huijsduijnen… - Nature Reviews Drug …, 2015 - nature.com
Despite substantial scientific progress over the past two decades, malaria remains a
worldwide burden that causes hundreds of thousands of deaths every year. New, affordable …

Protection against malaria by intravenous immunization with a nonreplicating sporozoite vaccine

RA Seder, LJ Chang, ME Enama, KL Zephir… - Science, 2013 - science.org
Consistent, high-level, vaccine-induced protection against human malaria has only been
achieved by inoculation of Plasmodium falciparum (Pf) sporozoites (SPZ) by mosquito bites …

Characterizing, controlling and eliminating residual malaria transmission

GF Killeen - Malaria journal, 2014 - Springer
Long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) interventions can
reduce malaria transmission by targeting mosquitoes when they feed upon slee** …

malERA: an updated research agenda for malaria elimination and eradication

RN Rabinovich, C Drakeley, AA Djimde, BF Hall… - PLoS …, 2017 - journals.plos.org
Achieving a malaria-free world presents exciting scientific challenges as well as
overwhelming health, equity, and economic benefits. WHO and countries are setting …

G6PD deficiency prevalence and estimates of affected populations in malaria endemic countries: a geostatistical model-based map

RE Howes, FB Piel, AP Patil, OA Nyangiri… - PLoS …, 2012 - journals.plos.org
Background Primaquine is a key drug for malaria elimination. In addition to being the only
drug active against the dormant relapsing forms of Plasmodium vivax, primaquine is the sole …

A Long Neglected World Malaria Map: Plasmodium vivax Endemicity in 2010

PW Gething, IRF Elyazar, CL Moyes, DL Smith… - 2012 - journals.plos.org
Background Current understanding of the spatial epidemiology and geographical
distribution of Plasmodium vivax is far less developed than that for P. falciparum …