Mesenchymal stem cells-derived exosomes for drug delivery

Y Sun, G Liu, K Zhang, Q Cao, T Liu, J Li - Stem cell research & therapy, 2021 - Springer
Exosomes are extracellular vesicles secreted by various cells, mainly composed of lipid
bilayers without organelles. In recent years, an increasing number of researchers have …

Preconditioning and Engineering Strategies for Improving the Efficacy of Mesenchymal Stem Cell‐Derived Exosomes in Cell‐Free Therapy

S Chen, F Sun, H Qian, W Xu, J Jiang - Stem cells international, 2022 - Wiley Online Library
Mesenchymal stem cells (MSCs) have been widely applied to regenerative medicine owing
to their multiple differentiation, self‐renewal, and immunomodulatory abilities. Exosomes are …

Mesenchymal stem cells derived extracellular vesicles: a promising nanomedicine for drug delivery system

J Rezaie, V Nejati, M Mahmoodi, M Ahmadi - Biochemical Pharmacology, 2022 - Elsevier
An ideal drug delivery system should selectively deliver incorporated therapeutics to the
target site, escape from immune cells recognition and degradation, and act controlled …

Advanced phytochemical-based nanocarrier systems for the treatment of breast cancer

VP Chavda, LV Nalla, P Balar, R Bezbaruah… - Cancers, 2023 - mdpi.com
Simple Summary Breast cancer is a concern for the healthcare system. Even with the
advancement of science and technology, the current system for therapeutics and diagnostics …

Exosome-based nanomedicine for cancer treatment by targeting inflammatory pathways: current status and future perspectives

MA Ansari, M Thiruvengadam, B Venkidasamy… - Seminars in cancer …, 2022 - Elsevier
Cancer is one of the dreadful diseases worldwide. Surgery, radiation and chemotherapy, are
the three basic standard modes of cancer treatment. However, difficulties in cancer treatment …

Research advances of engineered exosomes as drug delivery carrier

L Huang, E Wu, J Liao, Z Wei, J Wang, Z Chen - ACS omega, 2023 - ACS Publications
Exosomes are nanoscale vesicles secreted by living cells that have similar membrane
composition to parental cells and carry a variety of proteins, lipids, and nucleic acids …

Mesenchymal stem cell-derived exosomes in cancer therapy resistance: recent advances and therapeutic potential

Z Lin, Y Wu, Y Xu, G Li, Z Li, T Liu - Molecular cancer, 2022 - Springer
Mesenchymal stem cells (MSCs) are multipotent stromal cells that can be obtained from
various human tissues and organs. They can differentiate into a wide range of cell types …

Unlocking exosome-based theragnostic signatures: deciphering secrets of ovarian cancer metastasis

S Mukherjee, S Nag, N Mukerjee, S Maitra… - ACS …, 2023 - ACS Publications
Ovarian cancer (OC) is a common gynecological cancer worldwide. Unfortunately, the lack
of early detection methods translates into a substantial cohort of women grappling with the …

Exosomes; multifaceted nanoplatform for targeting brain cancers

N Mardi, F Salahpour-Anarjan, M Nemati, NS Baher… - Cancer letters, 2023 - Elsevier
At the moment, anaplastic changes within the brain are challenging due to the complexity of
neural tissue, leading to the inefficiency of therapeutic protocols. The existence of a cellular …

A human chorionic gonadotropin (hCG) delivery platform using engineered uterine exosomes to improve endometrial receptivity

H Hajipour, L Farzadi, L Roshangar, Z Latifi, H Kahroba… - Life sciences, 2021 - Elsevier
Aim Endometrial exosomes carry bioactive agents to uterine epithelial cells and
trophectoderm to promote implantation. On the other hand, intrauterine administration of …