The development of equine immunity: Current knowledge on immunology in the young horse

GA Perkins, B Wagner - Equine veterinary journal, 2015 - Wiley Online Library
The development of equine immunity from the fetus to adulthood is complex. The foal's
immune response and the immune mechanisms that they are equipped with, along with …

Intracellular cytokine detection by fluorescence-activated flow cytometry: basic principles and recent advances

G Freer, L Rindi - Methods, 2013 - Elsevier
Intracellular cytokine staining is a flow cytometric technique consisting of culturing stimulated
cytokine-producing cells in the presence of a protein secretion inhibitor, followed by fixation …

Equine Herpesviruses 14

J Slater - Equine Infectious Diseases E-Book: Equine Infectious …, 2013 - books.google.com
The equine herpesviruses (EHVs) are highly successful pathogens of all members of the
Equidae family worldwide. 1-4 Of the nine EHVs characterized thus far, five types (EHV-1 to …

Vaccination against equine influenza: quid novi?

R Paillot, D Hannant, JH Kydd, JM Daly - Vaccine, 2006 - Elsevier
Equine influenza virus is a leading cause of respiratory disease in the horse. Equine
influenza vaccines containing inactivated virus were first developed in the 1960s. Despite …

Equine herpes virus-1: virus, immunity and vaccines

R Paillot, R Case, J Ross, R Newton… - The Open Veterinary …, 2008 - benthamopen.com
Equine Herpes virus-1 (EHV-1) is one of the most common respiratory pathogens of the
horse. EHV-1 induces several clinical signs of disease ranging in severity, from mild …

Impact of the host immune response on the development of equine herpesvirus myeloencephalopathy in horses

KS Giessler, LS Goehring, SI Jacob… - Journal of General …, 2024 - microbiologyresearch.org
Herpesviruses establish a well-adapted balance with their host's immune system. Despite
this co-evolutionary balance, infections can lead to severe disease including neurological …

A West Nile virus (WNV) recombinant canarypox virus vaccine elicits WNV-specific neutralizing antibodies and cell-mediated immune responses in the horse

H El Garch, JM Minke, J Rehder, S Richard… - Veterinary immunology …, 2008 - Elsevier
Successful vaccination against West Nile virus (WNV) requires induction of both neutralizing
antibodies and cell-mediated immune responses. In this study, we have assessed the ability …

Antibody and cellular immune responses of naïve mares to repeated vaccination with an inactivated equine herpesvirus vaccine

B Wagner, LB Goodman, S Babasyan, H Freer… - Vaccine, 2015 - Elsevier
Abstract Equine herpesvirus type 1 (EHV-1) continues to cause severe outbreaks of
abortions or myeloencephalopathy in horses despite widely used vaccination. The aim of …

Evaluation of immune responses following infection of ponies with an EHV-1 ORF1/2 deletion mutant

GS Hussey, SB Hussey, B Wagner, DW Horohov… - Veterinary …, 2011 - Springer
Abstract Equine herpesvirus-1 (EHV-1) infection remains a significant problem despite the
widespread use of vaccines. The inability to generate a protective immune response to EHV …

[HTML][HTML] Interferon-gamma, interleukin-4 and interleukin-10 production by T helper cells reveals intact Th1 and regulatory TR1 cell activation and a delay of the Th2 …

B Wagner, A Burton, D Ainsworth - Veterinary research, 2010 - ncbi.nlm.nih.gov
Cytokines produced by T helper (Th) cells are important in orchestrating the immune
response during health and disease. Recent reports indicated that cytokine mRNA …