Smart and bioinspired systems for overcoming biological barriers and enhancing disease theranostics

X Li, Y Gao, H Li, JP Majoral, X Shi, A Pich - Progress in Materials Science, 2023 - Elsevier
Nanomedicine has emerged as a promising mean to improve theranostic efficacy and
reduce side effects. Currently, only very small percentage of injected dose reaches the solid …

Aggregation‐induced emission: the whole is more brilliant than the parts

J Mei, Y Hong, JWY Lam, A Qin, Y Tang… - Advanced …, 2014 - Wiley Online Library
“United we stand, divided we fall.”–Aesop. Aggregation‐induced emission (AIE) refers to a
photophysical phenomenon shown by a group of luminogenic materials that are non …

Glycomimetics versus multivalent glycoconjugates for the design of high affinity lectin ligands

S Cecioni, A Imberty, S Vidal - Chemical reviews, 2015 - ACS Publications
One could certainly highlight a conceptual resemblance between social interactions as the
basis of societies and civilizations and the ability of molecules to interact in a noncovalent …

Advancements in antimicrobial nanoscale materials and self-assembling systems

JA Doolan, GT Williams, KLF Hilton… - Chemical Society …, 2022 - pubs.rsc.org
Antimicrobial resistance is directly responsible for more deaths per year than either
HIV/AIDS or malaria and is predicted to incur a cumulative societal financial burden of at …

Carbohydrates in supramolecular chemistry

M Delbianco, P Bharate, S Varela-Aramburu… - Chemical …, 2016 - ACS Publications
Carbohydrates are involved in a variety of biological processes. The ability of sugars to form
a large number of hydrogen bonds has made them important components for …

Applications of discrete synthetic macromolecules in life and materials science: recent and future trends

R Aksakal, C Mertens, M Soete, N Badi… - Advanced …, 2021 - Wiley Online Library
In the last decade, the field of sequence‐defined polymers and related ultraprecise,
monodisperse synthetic macromolecules has grown exponentially. In the early stage, mainly …

FimH and anti-adhesive therapeutics: a disarming strategy against uropathogens

M Sarshar, P Behzadi, C Ambrosi, C Zagaglia… - Antibiotics, 2020 - mdpi.com
Chaperone-usher fimbrial adhesins are powerful weapons against the uropathogens that
allow the establishment of urinary tract infections (UTIs). As the antibiotic therapeutic …

Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes and other complex architectures with bioactivity to …

V Percec, P Leowanawat, HJ Sun… - Journal of the …, 2013 - ACS Publications
The modular synthesis of 7 libraries containing 51 self-assembling amphiphilic Janus
dendrimers with the monosaccharides d-mannose and d-galactose and the disaccharide d …

Organizing multivalency in carbohydrate recognition

C Müller, G Despras, TK Lindhorst - Chemical Society Reviews, 2016 - pubs.rsc.org
The interactions of cell surface carbohydrates as well as of soluble glycoconjugates with
their receptor proteins rule fundamental processes in cell biology. One of the …

Sulfated glycopeptide nanostructures for multipotent protein activation

SS Lee, T Fyrner, F Chen, Z Álvarez, E Sleep… - Nature …, 2017 - nature.com
Biological systems have evolved to utilize numerous proteins with capacity to bind
polysaccharides for the purpose of optimizing their function. A well-known subset of these …