[HTML][HTML] Fibroblasts: Origins, definitions, and functions in health and disease
Fibroblasts are diverse mesenchymal cells that participate in tissue homeostasis and
disease by producing complex extracellular matrix and creating signaling niches through …
disease by producing complex extracellular matrix and creating signaling niches through …
[HTML][HTML] Developmental origin of fat: tracking obesity to its source
The development of obesity not only depends on the balance between food intake and
caloric utilization but also on the balance between white adipose tissue, which is the primary …
caloric utilization but also on the balance between white adipose tissue, which is the primary …
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
Waist-hip ratio (WHR) is a measure of body fat distribution and a predictor of metabolic
consequences independent of overall adiposity. WHR is heritable, but few genetic variants …
consequences independent of overall adiposity. WHR is heritable, but few genetic variants …
Heterogeneity of adipose tissue in development and metabolic function
T Schoettl, IP Fischer, S Ussar - Journal of Experimental …, 2018 - journals.biologists.com
Adipose tissue is a central metabolic organ. Unlike other organs, adipose tissue is
compartmentalized into individual depots and distributed throughout the body. These …
compartmentalized into individual depots and distributed throughout the body. These …
Genetics, development and evolution of adaptive pigmentation in vertebrates
HE Hoekstra - Heredity, 2006 - nature.com
The study of pigmentation has played an important role in the intersection of evolution,
genetics, and developmental biology. Pigmentation's utility as a visible phenotypic marker …
genetics, and developmental biology. Pigmentation's utility as a visible phenotypic marker …
Evidence for a role of developmental genes in the origin of obesity and body fat distribution
S Gesta, M Blüher, Y Yamamoto… - Proceedings of the …, 2006 - National Acad Sciences
Obesity, especially central obesity, is a hereditable trait associated with a high risk for
development of diabetes and metabolic disorders. Combined gene expression analysis of …
development of diabetes and metabolic disorders. Combined gene expression analysis of …
The T-box gene family: emerging roles in development, stem cells and cancer
VE Papaioannou - Development, 2014 - journals.biologists.com
The T-box family of transcription factors exhibits widespread involvement throughout
development in all metazoans. T-box proteins are characterized by a DNA-binding motif …
development in all metazoans. T-box proteins are characterized by a DNA-binding motif …
T-box genes in vertebrate development
LA Naiche, Z Harrelson, RG Kelly… - Annu. Rev …, 2005 - annualreviews.org
The myriad developmental roles served by the T-box family of transcription factor genes defy
easy categorization. Present in all metazoans, the T-box genes are involved in early …
easy categorization. Present in all metazoans, the T-box genes are involved in early …
Signatures of archaic adaptive introgression in present-day human populations
Comparisons of DNA from archaic and modern humans show that these groups interbred,
and in some cases received an evolutionary advantage from doing so. This process …
and in some cases received an evolutionary advantage from doing so. This process …
Colours of domestication
M Cieslak, M Reissmann, M Hofreiter… - Biological …, 2011 - Wiley Online Library
During the last decade, coat colouration in mammals has been investigated in numerous
studies. Most of these studies addressing the genetics of coat colouration were on …
studies. Most of these studies addressing the genetics of coat colouration were on …