[HTML][HTML] Fibroblasts: Origins, definitions, and functions in health and disease

MV Plikus, X Wang, S Sinha, E Forte, SM Thompson… - Cell, 2021 - cell.com
Fibroblasts are diverse mesenchymal cells that participate in tissue homeostasis and
disease by producing complex extracellular matrix and creating signaling niches through …

[HTML][HTML] Developmental origin of fat: tracking obesity to its source

S Gesta, YH Tseng, CR Kahn - Cell, 2007 - cell.com
The development of obesity not only depends on the balance between food intake and
caloric utilization but also on the balance between white adipose tissue, which is the primary …

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

IM Heid, AU Jackson, JC Randall, TW Winkler, L Qi… - Nature …, 2010 - nature.com
Waist-hip ratio (WHR) is a measure of body fat distribution and a predictor of metabolic
consequences independent of overall adiposity. WHR is heritable, but few genetic variants …

Heterogeneity of adipose tissue in development and metabolic function

T Schoettl, IP Fischer, S Ussar - Journal of Experimental …, 2018 - journals.biologists.com
Adipose tissue is a central metabolic organ. Unlike other organs, adipose tissue is
compartmentalized into individual depots and distributed throughout the body. These …

Genetics, development and evolution of adaptive pigmentation in vertebrates

HE Hoekstra - Heredity, 2006 - nature.com
The study of pigmentation has played an important role in the intersection of evolution,
genetics, and developmental biology. Pigmentation's utility as a visible phenotypic marker …

Evidence for a role of developmental genes in the origin of obesity and body fat distribution

S Gesta, M Blüher, Y Yamamoto… - Proceedings of the …, 2006 - National Acad Sciences
Obesity, especially central obesity, is a hereditable trait associated with a high risk for
development of diabetes and metabolic disorders. Combined gene expression analysis of …

The T-box gene family: emerging roles in development, stem cells and cancer

VE Papaioannou - Development, 2014 - journals.biologists.com
The T-box family of transcription factors exhibits widespread involvement throughout
development in all metazoans. T-box proteins are characterized by a DNA-binding motif …

T-box genes in vertebrate development

LA Naiche, Z Harrelson, RG Kelly… - Annu. Rev …, 2005 - annualreviews.org
The myriad developmental roles served by the T-box family of transcription factor genes defy
easy categorization. Present in all metazoans, the T-box genes are involved in early …

Signatures of archaic adaptive introgression in present-day human populations

F Racimo, D Marnetto… - Molecular biology and …, 2017 - academic.oup.com
Comparisons of DNA from archaic and modern humans show that these groups interbred,
and in some cases received an evolutionary advantage from doing so. This process …

Colours of domestication

M Cieslak, M Reissmann, M Hofreiter… - Biological …, 2011 - Wiley Online Library
During the last decade, coat colouration in mammals has been investigated in numerous
studies. Most of these studies addressing the genetics of coat colouration were on …