In the last decade, molecular dynamics (MD) simulations have become an essential tool to
investigate the molecular properties of membrane trafficking processes, often in conjunction …

Autophagy–the lysosomal degradation of cytoplasm–plays a central role in cellular
homeostasis and protects cells from potentially harmful agents that may accumulate in the …

Cells use noncanonical autophagy, also called conjugation of ATG8 to single membranes
(CASM), to label damaged intracellular compartments with ubiquitin‐like ATG8 family …

The covalent attachment of ubiquitin-like LC3 proteins (microtubule-associated proteins
1A/1B light chain 3) prepares the autophagic membrane for cargo recruitment. We resolve …

Autophagosome biogenesis requires a localized perturbation of lipid membrane dynamics
and a unique protein-lipid conjugate. Autophagy-related (ATG) proteins catalyze this …

An increasing corpus of research has demonstrated that membrane shape, generated either
by the external environment of the cell or by intrinsic mechanisms such as cytokinesis and …

One of the key events in autophagy is the formation of a double-membrane phagophore,
and many regulatory mechanisms underpinning this remain under investigation. WIPI2b is …

Curvature sensing is an essential ability of biomolecules to preferentially localize to
membrane regions of a specific curvature. It has been shown that amphipathic helices …

We present FreeDTS software for performing computational research on biomembranes at
the mesoscale. In this software, a membrane is represented by a dynamically triangulated …

Rough endoplasmic reticulum (ER) sheets are a fundamental domain of the ER and the
gateway into the secretory pathway. Although reticulon proteins stabilize high-curvature ER …