Misfolded proteins in the central nervous system can induce oxidative damage, which can
contribute to neurodegenerative diseases in the mitochondria. Neurodegenerative patients …

Alzheimer's disease (AD) is the main type of dementia and is a disease with a profound
socioeconomic burden due to the lack of effective treatment. In addition to genetics and …

Objective Alzheimer's disease (AD) is a global health problem without effective methods to
alleviate the disease progression. Amyloid β-protein (Aβ) is widely accepted as a key …

Cognitive decline in chronic diabetic patients is a less investigated topic. Diabetes and
obesity are among the modifiable risk factors for Alzheimer's disease (AD), the most …

Alzheimer's disease (AD) is the most common form of dementia in the elderly followed by
vascular dementia. In addition to clinically diagnosed dementia, cognitive dysfunction has …

Metabolic syndrome (MetS), which is characterized by insulin resistance, high blood
glucose, obesity, and dyslipidemia, is known to increase the risk of dementia accompanied …

The increase in human life expectancy has become a challenge to reduce the deleterious
consequences of aging. Nowadays, an increasing number of the population suffer from age …

Alzheimer disease (AD) is the most common form of dementia among the elderly and is
characterized by progressive loss of memory and cognition. Epidemiological data show that …

Alpha-lipoic acid is a naturally occurring substance, essential for the function of different
enzymes that take part in mitochondria's oxidative metabolism. It is believed that alpha-lipoic …

Alzheimer's disease (AD) is a fatal neurodegenerative disease in which senile plaques and
neurofibrillary tangles are crucially involved in its physiological and pathophysiological …