Liquid biopsy in cancer current: status, challenges and future prospects
L Ma, H Guo, Y Zhao, Z Liu, C Wang, J Bu… - … and Targeted Therapy, 2024 - nature.com
Cancer has a high mortality rate across the globe, and tissue biopsy remains the gold
standard for tumor diagnosis due to its high level of laboratory standardization, good …
standard for tumor diagnosis due to its high level of laboratory standardization, good …
Droplet-based digital PCR and next generation sequencing for monitoring circulating tumor DNA: a cancer diagnostic perspective
M Postel, A Roosen, P Laurent-Puig… - Expert review of …, 2018 - Taylor & Francis
Introduction: Early detection of cancers through the analysis of ctDNA could have a
significant impact on morbidity and mortality of cancer patients. However, using ctDNA for …
significant impact on morbidity and mortality of cancer patients. However, using ctDNA for …
Personalized ctDNA for monitoring disease status in head and neck squamous cell carcinoma
GJ Hanna, MJ Dennis, N Scarfo, MS Mullin… - Clinical Cancer …, 2024 - aacrjournals.org
Purpose: Many patients with locoregionally advanced human papillomavirus–negative head
and neck squamous cell carcinoma (HNSCC) relapse. ctDNA has the potential to identify …
and neck squamous cell carcinoma (HNSCC) relapse. ctDNA has the potential to identify …
Serum, plasma and saliva biomarkers for head and neck cancer
LMRB Arantes, AC De Carvalho… - Expert review of …, 2018 - Taylor & Francis
Introduction: Head and neck squamous cell carcinoma (HNSCC) encompasses tumors
arising from several locations (oral and nasal cavities, paranasal sinuses, salivary glands …
arising from several locations (oral and nasal cavities, paranasal sinuses, salivary glands …
New perspectives on the importance of cell-free DNA biology
Body fluids are constantly replenished with a population of genetically diverse cell-free DNA
(cfDNA) fragments, representing a vast reservoir of information reflecting real-time changes …
(cfDNA) fragments, representing a vast reservoir of information reflecting real-time changes …
Malignancies and biosensors: A focus on oral cancer detection through salivary biomarkers
Oral cancer is among the deadliest types of malignancy due to the late stage at which it is
usually diagnosed, leaving the patient with an average five-year survival rate of less than …
usually diagnosed, leaving the patient with an average five-year survival rate of less than …
Epigenetic biomarkers in cell-free DNA and applications in liquid biopsy
Cell-free circulating DNA (cfDNA) in plasma has gained global interest as a diagnostic
material for noninvasive prenatal testing and cancer diagnosis, or the so-called “liquid …
material for noninvasive prenatal testing and cancer diagnosis, or the so-called “liquid …
Promoter methylation of SEPT9 as a potential biomarker for early detection of cervical cancer and its overexpression predicts radioresistance
X Jiao, S Zhang, J Jiao, T Zhang, W Qu, GM Muloye… - Clinical …, 2019 - Springer
Background Cervical cancer screening by combined cytology and HPV test has reduced the
incidence of cervical cancer, but cytological screening lacks a higher sensitivity while HPV …
incidence of cervical cancer, but cytological screening lacks a higher sensitivity while HPV …
Liquid biopsy in oral cancer
F Lousada-Fernandez, O Rapado-Gonzalez… - International journal of …, 2018 - mdpi.com
Oral cancer is one of the most prevalent forms of cancer worldwide. Carcinogenesis is a
complex process, in which heterogeneity plays an important role in the development and …
complex process, in which heterogeneity plays an important role in the development and …
Circulating tumour DNA alterations: emerging biomarker in head and neck squamous cell carcinoma
Head and Neck cancers (HNC) are a heterogeneous group of upper aero-digestive tract
cancer and account for 931,922 new cases and 467,125 deaths worldwide. About 90% of …
cancer and account for 931,922 new cases and 467,125 deaths worldwide. About 90% of …