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Potassium channels: molecular defects, diseases, and therapeutic opportunities
CC Shieh, M Coghlan, JP Sullivan… - Pharmacological …, 2000 - Elsevier
Potassium channels play important roles in vital cellular signaling processes in both
excitable and nonexcitable cells. Over 50 human genes encoding various K+ channels have …
excitable and nonexcitable cells. Over 50 human genes encoding various K+ channels have …
Molecular psychology: roles for the ERK MAP kinase cascade in memory
JP Adams, JD Sweatt - Annual review of pharmacology and …, 2002 - annualreviews.org
In this review we describe an emerging understanding of the roles of the Extracellular-signal
regulated kinase/mitogen-activated protein kinase (ERK/MAPK) cascade in learning and …
regulated kinase/mitogen-activated protein kinase (ERK/MAPK) cascade in learning and …
[HTML][HTML] K+ channel regulation of signal propagation in dendrites of hippocampal pyramidal neurons
Pyramidal neurons receive tens of thousands of synaptic inputs on their dendrites. The
dendrites dynamically alter the strengths of these synapses and coordinate them to produce …
dendrites dynamically alter the strengths of these synapses and coordinate them to produce …
Modulation of A-type potassium channels by a family of calcium sensors
WF An, MR Bowlby, M Betty, J Cao, HP Ling… - Nature, 2000 - nature.com
In the brain and heart, rapidly inactivating (A-type) voltage-gated potassium (Kv) currents
operate at subthreshold membrane potentials to control the excitability of neurons and …
operate at subthreshold membrane potentials to control the excitability of neurons and …
Structure and function of Kv4-family transient potassium channels
Shal-type (Kv4. x) K+ channels are expressed in a variety of tissue, with particularly high
levels in the brain and heart. These channels are the primary subunits that contribute to …
levels in the brain and heart. These channels are the primary subunits that contribute to …
The CD26-related dipeptidyl aminopeptidase-like protein DPPX is a critical component of neuronal A-type K+ channels
Subthreshold-activating somatodendritic A-type potassium channels have fundamental roles
in neuronal signaling and plasticity which depend on their unique cellular localization …
in neuronal signaling and plasticity which depend on their unique cellular localization …
Differential Expression of Kv4 K+ Channel Subunits Mediating Subthreshold Transient K+ (A-Type) Currents in Rat Brain
Serôdio, Paulo and Bernardo Rudy. Differential expression of Kv4 K+ channel subunits
mediating subthreshold transient K+ (A-type) currents in rat brain. J. Neurophysiol. 79: 1081 …
mediating subthreshold transient K+ (A-type) currents in rat brain. J. Neurophysiol. 79: 1081 …
Role of the Kv4.3 K+ Channel in Ventricular Muscle: A Molecular Correlate for the Transient Outward Current
The expression of 15 different K+ channels in canine heart was examined, and a new K+
channel gene (Kv4. 3), which encodes a rapidly inactivating K+ current, is described. The …
channel gene (Kv4. 3), which encodes a rapidly inactivating K+ current, is described. The …
Downregulation of transient K+ channels in dendrites of hippocampal CA1 pyramidal neurons by activation of PKA and PKC
We have reported recently a high density of transient A-type K+ channels located in the
distal dendrites of CA1 hippocampal pyramidal neurons and shown that these channels …
distal dendrites of CA1 hippocampal pyramidal neurons and shown that these channels …
Contributions of Kv3 channels to neuronal excitability
Four mammalian Kv3 genes have been identified, each of which generates, by alternative
splicing, multiple protein products differing in their C‐terminal sequence. Products of the …
splicing, multiple protein products differing in their C‐terminal sequence. Products of the …