In recent years, fatty acid binding protein 5 (FABP5), also known as fatty acid transporter,
has been widely researched with the help of modern genetic technology. Emerging …

Highlights•Fatty acid binding protein 5 (FABP5) is a key regulator of cell metabolism and
growth that is overexpressed in cancers.•FABP5 facilitates the activation of transcriptional …

First identified in the early 1980s as retroviral oncogenes, the Raf proteins have been the
objects of intense research. The discoveries 10 years later that the Raf family members (Raf …

The link between perturbations in translational control and cancer etiology is becoming a
primary focus in cancer research. It has now been established that genetic alterations in …

Eukaryotic gene expression is a complicated process primarily regulated at the levels of
gene transcription and mRNA translation. The latter involves four main steps: initiation …

Simple Summary Head and neck squamous cell carcinoma is one of the most common
cancers that arises in the upper aerodigestive tract. Patients suffering from this cancer have …

The heterogeneous nuclear ribonucleoproteins (hnRNP) are a family of proteins which
share common structural domains, and extensive research has shown that they have central …

The eukaryotic initiation factor 3 (eIF3) is one of the most complex translation initiation
factors in mammalian cells, consisting of several subunits (eIF3a to eIF3m). It is crucial in …

Specific individual subunits of eIF3 are elevated or reduced in numerous human tumors, and
their ectopic overexpression in immortal cells can result in malignant transformation. The …

Recent technological advancements have shown tremendous mechanistic
accomplishments in our understanding of the mechanism of messenger RNA translation in …