Laboratory diagnostics for human Leishmania infections: a polymerase chain reaction-focussed review of detection and identification methods

I Gow, NC Smith, D Stark, J Ellis - Parasites & Vectors, 2022 - Springer
Leishmania infections span a range of clinical syndromes and impact humans from many
geographic foci, but primarily the world's poorest regions. Transmitted by the bite of a female …

Cytokine saga in visceral leishmaniasis

R Bhor, S Rafati, K Pai - Cytokine, 2021 - Elsevier
In humans, infection with Leishmania manifests into a spectrum of diseases. The
manifestation of the diseases depend on the resultant evasion of the parasite to immune …

Parasite genotype is a major predictor of mortality from visceral leishmaniasis

CA Grace, KS Sousa Carvalho, MI Sousa Lima… - MBio, 2022 - Am Soc Microbiol
Visceral leishmaniasis (VL) is a potentially fatal disease caused mainly by Leishmania
infantum in South America and Leishmania donovani in Asia and Africa. Disease outcomes …

Candidates for Balancing Selection in Leishmania donovani Complex Parasites

CA Grace, S Forrester, VC Silva… - Genome biology and …, 2021 - academic.oup.com
The Leishmania donovani species complex is the causative agent of visceral leishmaniasis,
which cause 20–40,000 fatalities a year. Here, we conduct a screen for balancing selection …

Assembly of a Large Collection of Maxicircle Sequences and Their Usefulness for Leishmania Taxonomy and Strain Ty**

JC Solana, C Chicharro, E García, B Aguado, J Moreno… - Genes, 2022 - mdpi.com
Parasites of medical importance, such as Leishmania and Trypanosoma, are characterized
by the presence of thousands of circular DNA molecules forming a structure known as …

Genome wide mining of SNPs and INDELs through ddRAD sequencing in Sahiwal cattle

TV Raja, R Alex, U Singh, S Kumar, AK Das… - Animal …, 2023 - Taylor & Francis
The study was conducted in Sahiwal cattle for genome wide identification and annotation of
single nucleotide polymorphisms (SNPs) and insertions and deletions (INDELs) in Sahiwal …

Revisiting the heterogeneous global genomic population structure of Leishmania infantum

LH Patino, A Castillo-Castañeda… - Microbial …, 2021 - microbiologyresearch.org
Leishmania infantum is the main causative agent responsible for visceral leishmaniasis
(VL), a disease with global distribution. The genomic structure and genetic variation of this …

[HTML][HTML] Whole genome resequencing unveils low-temperature stress tolerance specific genomic variations in jute (Corchorus sp.)

A Ganguly, S Amin, FT Chowdhury, H Khan… - Journal of Genetic …, 2024 - Elsevier
Abstract Jute (Corchorus sp.), a commercially important and eco-friendly crop, is widely
cultivated in Bangladesh, India, and China. Some varieties of this tropical plant such as the …

Genome-wide analysis reveals allelic variation and chromosome copy number variation in paromomycin-resistant Leishmania donovani

S Ghosh, V Kumar, A Verma, T Sharma, D Pradhan… - Parasitology …, 2022 - Springer
In the absence of adequate diagnosis and treatment, leishmaniasis remains a major public
health concern on a global scale. Drug resistance remains a key obstacle in controlling and …

Uncovering hidden genetic risk factors for breast and ovarian cancers in BRCA-negative women: a machine learning approach in the Saudi population

N Alganmi, A Bashanfar, R Alotaibi, H Banjar… - PeerJ Computer …, 2024 - peerj.com
Breast and ovarian cancers are prevalent worldwide, with genetic factors such as BRCA1
and BRCA2 mutations playing a significant role. However, not all patients carry these …