Variation within the non-coding genome influences genetic and epigenetic regulation of the human leukocyte antigen genes
T Arumugam, T Adimulam, A Gokul… - Frontiers in …, 2024 - frontiersin.org
Variation within the non-coding genome may influence the regulation and expression of
important genes involved in immune control such as the human leukocyte antigen (HLA) …
important genes involved in immune control such as the human leukocyte antigen (HLA) …
Exploring the HLA complex in autoimmunity: From the risk haplotypes to the modulation of expression
S Sartoris, G Del Pozzo - Clinical Immunology, 2024 - Elsevier
The genes map** at the HLA region show high density, strong linkage disequilibrium and
high polymorphism, which affect the association of HLA class I and class II genes with …
high polymorphism, which affect the association of HLA class I and class II genes with …
Reassessment of marker genes in human induced pluripotent stem cells for enhanced quality control
Human induced pluripotent stem cells (iPSCs) have great potential in research, but
pluripotency testing faces challenges due to non-standardized methods and ambiguous …
pluripotency testing faces challenges due to non-standardized methods and ambiguous …
Assessing radish health during space cultivation by gene transcription
During the Advanced Plant Habitat experiment 2, radish plants were grown in two
successive grow-outs on the International Space Station (ISS) for 27 days each. On days 10 …
successive grow-outs on the International Space Station (ISS) for 27 days each. On days 10 …
[HTML][HTML] Identification and characterization of two salmon louse heme peroxidases and their potential as vaccine antigens
E Gislefoss, AAA Gamil, AC Øvergård, Ø Evensen - Iscience, 2023 - cell.com
Salmon louse, Lepeophtheirus salmonis, represents major challenge for salmon farming.
Current treatments impose welfare issues and are costly, whereas prophylactic measures …
Current treatments impose welfare issues and are costly, whereas prophylactic measures …
A hierarchical GNN across semantic and topological domains for predicting circRNA-microRNA interactions
Identifying circRNA-microRNA interactions (CMI) is a significant biomedical issue in recent
years. This problem provides insights into using circRNA as biomarkers, develo** cancer …
years. This problem provides insights into using circRNA as biomarkers, develo** cancer …
Establishment and comparison of human term placenta–derived trophoblast cells
Research on the biology of fetal–maternal barriers has been limited by access to
physiologically relevant cells, including trophoblast cells. In this study, we describe the …
physiologically relevant cells, including trophoblast cells. In this study, we describe the …
Nucleotide alterations in the HLA-C class I gene can cause aberrant splicing and marked changes in RNA levels in a polymorphic context-dependent manner
A Mizutani, S Suzuki, A Shigenari, T Sato… - Frontiers in …, 2024 - frontiersin.org
Polymorphisms of HLA genes, which play a crucial role in presenting peptides with diverse
sequences in their peptide-binding pockets, are also thought to affect HLA gene expression …
sequences in their peptide-binding pockets, are also thought to affect HLA gene expression …
Phenotypic and gene expression characteristics of Japanese eel late-stage leptocephali and glass eels after growth on different diets with a focus on nutrient …
R Hatakeyama, M Mekuchi, H Furuita, M Satomi… - Aquaculture, 2025 - Elsevier
To evaluate the quality of glass eels that were derived from late-stage Anguilla japonica
leptocephali raised on an old-type of shark egg-based diet (SE) or a new-type of fish meal …
leptocephali raised on an old-type of shark egg-based diet (SE) or a new-type of fish meal …
[HTML][HTML] A Snapshot of Early Transcriptional Changes Accompanying the Pro-Neural Phenotype Switch by NGN2, ASCL1, SOX2, and MSI1 in Human Fibroblasts: An …
EM Samoilova, DA Chudakova… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Direct pro-neural reprogramming is a conversion of differentiated somatic cells to neural
cells without an intermediate pluripotency stage. It is usually achieved via ectopic …
cells without an intermediate pluripotency stage. It is usually achieved via ectopic …