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The role of structure in regulatory RNA elements
JN Tants, A Schlundt - Bioscience reports, 2024 - portlandpress.com
Regulatory RNA elements fulfill functions such as translational regulation, control of
transcript levels, and regulation of viral genome replication. Trans-acting factors (ie, RNA …
transcript levels, and regulation of viral genome replication. Trans-acting factors (ie, RNA …
[HTML][HTML] Probing RNA structure and dynamics using nanopore and next generation sequencing
It has become increasingly evident that the structures RNAs adopt are conformationally
dynamic; the various structured states that RNAs sample govern their interactions with other …
dynamic; the various structured states that RNAs sample govern their interactions with other …
[HTML][HTML] Age and 17β-Estradiol (E2) Facilitate Nuclear Export and Argonaute Loading of microRNAs in the Female Brain
ML Linscott, Y Yildiz, S Flury, ML Newby, TR Pak - Non-coding RNA, 2023 - mdpi.com
Aging in women is accompanied by a dramatic change in circulating sex steroid hormones.
Specifically, the primary circulating estrogen, 17β-estradiol (E2), is nearly undetectable in …
Specifically, the primary circulating estrogen, 17β-estradiol (E2), is nearly undetectable in …
SRSF3 shapes the structure of miR‐17‐92 cluster RNA and promotes selective processing of miR‐17 and miR‐20a
MicroRNA (miRNA) biogenesis is tightly regulated to maintain distinct miRNA expression
patterns. Almost half of mammalian miRNAs are generated from miRNA clusters, but this …
patterns. Almost half of mammalian miRNAs are generated from miRNA clusters, but this …
Regulatory mechanisms through RNA conformational switching and dynamics
The last few years have deepened our appreciation of RNA as a magical molecule. RNA
serves as an enzyme (ribozyme) and receptor (riboswitch). It is essential for gene editing …
serves as an enzyme (ribozyme) and receptor (riboswitch). It is essential for gene editing …
[HTML][HTML] Advances and Obstacles in Using CRISPR/Cas9 Technology for Non-Coding RNA Gene Knockout in Human Mesenchymal Stromal Cells
N Basalova, M Illarionova, M Skryabina, M Vigovskiy… - Non-coding RNA, 2023 - mdpi.com
Non-coding RNA (ncRNAs) genes have attracted increasing attention in recent years due to
their widespread involvement in physiological and pathological processes and regulatory …
their widespread involvement in physiological and pathological processes and regulatory …
Roquin exhibits opposing effects on RNA stem-loop stability through its two ROQ domain binding sites
JN Tants, A Walbrun, L Kollwitz, K Friedrich, M Rief… - bioRxiv, 2024 - biorxiv.org
The interaction of mRNA and regulatory proteins is critical for post-transcriptional control. For
proper function, these interactions as well as the involved protein and RNA structures are …
proper function, these interactions as well as the involved protein and RNA structures are …
A New Insight of MicroRNA-96 In Human Malignant Disorders and Drug Resistance
Abstract miRNA-96 is a short non-coding RNA molecule which plays an essential function in
the regulation of post-transcriptional gene, and play a role in the development of a number …
the regulation of post-transcriptional gene, and play a role in the development of a number …