Epigenetic mechanisms of rapid-acting antidepressants
Abstract Background Rapid-acting antidepressants (RAADs), including dissociative
anesthetics, psychedelics, and empathogens, elicit rapid and sustained therapeutic …
anesthetics, psychedelics, and empathogens, elicit rapid and sustained therapeutic …
[HTML][HTML] Assessing the risk of symptom worsening in psilocybin-assisted therapy for depression: A systematic review and individual participant data meta-analysis
We conducted a meta-analysis using individual participant data from three, two-dose
psilocybin trials for depression (N= 102) with the aim of assessing the risk of symptom …
psilocybin trials for depression (N= 102) with the aim of assessing the risk of symptom …
Co-use of MDMA with psilocybin/LSD may buffer against challenging experiences and enhance positive experiences
Psilocybin and lysergic acid diethylamide (LSD) experiences can range from very positive to
highly challenging (eg, fear, grief, and paranoia). These challenging experiences contribute …
highly challenging (eg, fear, grief, and paranoia). These challenging experiences contribute …
How does psilocybin therapy work? An exploration of experiential avoidance as a putative mechanism of change
Background Psilocybin therapy is receiving attention as a mental health intervention with
transdiagnostic potential. In line with psychotherapeutic research, qualitative research has …
transdiagnostic potential. In line with psychotherapeutic research, qualitative research has …
[HTML][HTML] At-home, sublingual ketamine telehealth is a safe and effective treatment for moderate to severe anxiety and depression: findings from a large, prospective …
Abstract Background At-home Ketamine-assisted therapy (KAT) with psychosocial support
and remote monitoring through telehealth platforms addresses access barriers, including the …
and remote monitoring through telehealth platforms addresses access barriers, including the …
Race and ethnicity moderate the associations between lifetime psychedelic use (MDMA and psilocybin) and psychological distress and suicidality
Psychedelic compounds have been linked to salutary mental health outcomes in both
naturalistic and clinical settings; however, current research on psychedelics suffers from a …
naturalistic and clinical settings; however, current research on psychedelics suffers from a …
Social identity processes as a vehicle for therapeutic success in psychedelic treatment
The recent surge in psychedelics research has identified promising therapeutic uses for
conditions including anxiety, post-traumatic stress disorder, anorexia, depression, and …
conditions including anxiety, post-traumatic stress disorder, anorexia, depression, and …
Therapeutic (Sub) stance: Current practice and therapeutic conduct in preparatory sessions in substance-assisted psychotherapy—A systematized review
Background: Clinical trials are currently investigating the potential of substance-assisted
psychotherapy (SAPT) as treatment for several psychiatric conditions. The potential …
psychotherapy (SAPT) as treatment for several psychiatric conditions. The potential …
Safety and risk assessment of psychedelic psychotherapy: a meta-analysis and systematic review
B Romeo, E Kervadec, B Fauvel, L Strika-Bruneau… - Psychiatry …, 2024 - Elsevier
Psychotherapies assisted by psychedelic substances have shown promising results in the
treatment of psychiatric disorders. The aim of this systematic review and meta-analysis was …
treatment of psychiatric disorders. The aim of this systematic review and meta-analysis was …
Psychiatric risks for worsened mental health after psychedelic use
Background: Resurgent psychedelic research has largely supported the safety and efficacy
of psychedelic therapy for the treatment of various psychiatric disorders. As psychedelic use …
of psychedelic therapy for the treatment of various psychiatric disorders. As psychedelic use …