Autophagy in animal development

EA Allen, EH Baehrecke - Cell Death & Differentiation, 2020 - nature.com
Macroautophagy (autophagy) delivers intracellular constituents to the lysosome to promote
catabolism. During development in multiple organisms, autophagy mediates various cellular …

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

New insights on intermediary metabolism for a better understanding of nutrition in teleosts

S Panserat, L Marandel, I Seiliez… - Annual review of …, 2019 - annualreviews.org
The rapid development of aquaculture production throughout the world over the past few
decades has led to the emergence of new scientific challenges to improve fish nutrition. The …

Autophagy in SDF-1α-mediated DPSC migration and pulp regeneration

J Yang, Y Zhang, C Wan, Z Sun, S Nie, S Jian, L Zhang… - Biomaterials, 2015 - Elsevier
Critical morphological requirements for pulp regeneration are tissues replete with
vascularisation, neuron formation, and dentin deposition. Autophagy was recently shown to …

The STAT3–IL-10–IL-6 pathway is a novel regulator of macrophage efferocytosis and phenotypic conversion in sterile liver injury

L Campana, PJ Starkey Lewis, A Pellicoro… - The Journal of …, 2018 - journals.aai.org
The disposal of apoptotic bodies by professional phagocytes is crucial to effective
inflammation resolution. Our ability to improve the disposal of apoptotic bodies by …

In vivo monitoring of tissue regeneration using a ratiometric lysosomal AIE probe

X Shi, N Yan, G Niu, SHP Sung, Z Liu, J Liu… - Chemical …, 2020 - pubs.rsc.org
Tissue regeneration is a crucial self-renewal capability involving many complex biological
processes. Although transgenic techniques and fluorescence immunohistochemical staining …

Up-regulation of autophagy-related gene 5 (ATG5) protects dopaminergic neurons in a zebrafish model of Parkinson's disease

Z Hu, B Chen, J Zhang, Y Ma - Journal of Biological Chemistry, 2017 - ASBMB
Parkinson's disease (PD) is one of the most epidemic neurodegenerative diseases and is
characterized by movement disorders arising from loss of midbrain dopaminergic (DA) …

1-phenyl 2-thiourea (PTU) activates autophagy in zebrafish embryos

XK Chen, JSK Kwan, RCC Chang, ACH Ma - Autophagy, 2021 - Taylor & Francis
phenyl 2-thiourea (PTU) is a Tyr (tyrosinase) inhibitor that is extensively used to block
pigmentation and improve optical transparency in zebrafish (Danio rerio) embryo. Here, we …

Dynamic gene expression by putative hair-cell progenitors during regeneration in the zebrafish lateral line

AB Steiner, T Kim, V Cabot… - Proceedings of the …, 2014 - National Acad Sciences
Hearing loss is most commonly caused by the destruction of mechanosensory hair cells in
the ear. This condition is usually permanent: Despite the presence of putative hair-cell …

Studying autophagy in zebrafish

BJ Mathai, AH Meijer, A Simonsen - Cells, 2017 - mdpi.com
Autophagy is an evolutionarily conserved catabolic process which allows lysosomal
degradation of complex cytoplasmic components into basic biomolecules that are recycled …