[HTML][HTML] Imidazoles as potential anticancer agents: An update on recent studies

P Sharma, C LaRosa, J Antwi, R Govindarajan… - Molecules, 2021 - mdpi.com
Nitrogen-containing heterocyclic rings are common structural components of marketed
drugs. Among these heterocycles, imidazole/fused imidazole rings are present in a wide …

Evaluation of metal-based antimicrobial compounds for the treatment of bacterial pathogens

A Evans, KA Kavanagh - Journal of medical microbiology, 2021 - microbiologyresearch.org
Antimicrobial resistance (AMR) is one of the greatest global health challenges of modern
times and its prevalence is rising worldwide. AMR within bacteria reduces the efficacy of …

Development of membrane-targeting fluorescent 2-phenyl-1 h-phenanthro [9, 10-d] imidazole-antimicrobial peptide mimic conjugates against methicillin-resistant …

T Xu, X Yan, A Kang, L Yang, X Li, Y Tian… - Journal of Medicinal …, 2024 - ACS Publications
The escalation of multidrug-resistant bacterial infections, especially infections caused by
methicillin-resistant Staphylococcus aureus (MRSA), underscores the urgent need for novel …

Extensive impact of non-antibiotic drugs on human gut bacteria

L Maier, M Pruteanu, M Kuhn, G Zeller, A Telzerow… - Nature, 2018 - nature.com
A few commonly used non-antibiotic drugs have recently been associated with changes in
gut microbiome composition, but the extent of this phenomenon is unknown. Here, we …

Comprehensive insights into medicinal research on imidazole-based supramolecular complexes

SR Li, YM Tan, L Zhang, CH Zhou - Pharmaceutics, 2023 - mdpi.com
The electron-rich five-membered aromatic aza-heterocyclic imidazole, which contains two
nitrogen atoms, is an important functional fragment widely present in a large number of …

In situ Ag-MOF growth on pre-grafted zwitterions imparts outstanding antifouling properties to forward osmosis membranes

M Pejman, M Dadashi Firouzjaei… - … applied materials & …, 2020 - ACS Publications
In this study, a polyamide forward osmosis membrane was functionalized with zwitterions
followed by the in situ growth of metal–organic frameworks with silver as a metal core (Ag …

New progress in azole compounds as antimicrobial agents

HZ Zhang, LL Gan, H Wang… - Mini reviews in medicinal …, 2017 - ingentaconnect.com
The increasing incidence of microbial resistance and newly emerging pathogens have
become a serious challenge for public health. More and more efforts have been directed to …

[HTML][HTML] Imidazole-pyridine hybrids as potent anti-cancer agents

B Aruchamy, C Drago, V Russo, GM Pitari… - European Journal of …, 2023 - Elsevier
In the current investigation, fifteen novel imidazole-pyridine-based molecules were
synthesized and tested against cell lines of the lung (H1299) and colon (HCT116) …

Electrochemical multicomponent [2+ 2+ 1] cascade cyclization of enaminones and primary amines towards the synthesis of 4-acylimidazoles

M Wang, Y Gao, XJ Zhao, L Gao, Y He - Chemical Communications, 2024 - pubs.rsc.org
An electrochemical multicomponent [2+ 2+ 1] cascade cyclization of enaminones and
primary amines towards the synthesis of 4-acylimidazoles has been developed. In an …

Design and preparation of ZnS‐ZnFe2O4: a green and efficient hybrid nanocatalyst for the multicomponent synthesis of 2,4,5‐triaryl‐1H‐imidazoles

Z Varzi, A Maleki - Applied Organometallic Chemistry, 2019 - Wiley Online Library
In the present work, a new protocol was introduced for the preparation of an efficient hybrid
nanocatalyst ZnS‐ZnFe2O4 via the co‐precipitation method as well as its application in the …