Programmed cell death (PCD, mainly including apoptosis, necrosis, ferroptosis, pyroptosis,
and autophagy) and immunogenic cell death (ICD), as important cell death mechanisms, are …

Camptothecin (CPT) is a cytotoxic alkaloid that attenuates the replication of cancer cells via
blocking DNA topoisomerase 1. Despite its encouraging and wide-spectrum antitumour …

Azide-alkyne cycloaddition reaction is a very common organic reaction to synthesize
nitrogen-containing heterocycles. Once catalyzed by Cu (I) or Ru (II), it turns out to be a click …

In vivo cross‐linking of nanoparticles is widely used to increase accumulation of therapeutic
agents at tumor site for enhanced therapy. However, the components in nanoplatforms …

Staphylococcus aureus (S. aureus) is able to hide within host cells to escape immune
clearance and antibiotic action, causing life‐threatening infections. To boost the therapeutic …

Immunotherapy has attracted widespread attention in cancer treatment and has achieved
considerable success in the clinical treatment of some tumors, but it has a low response rate …

Immunotherapy has received widespread attention for its effective and long‐term tumor‐
eliminating ability. However, for immunogenic “cold” tumors, such as prostate cancer (PCa) …

Cancer is a major public health concern requiring novel treatment approaches. Enzyme-
instructed self-assembly (EISA) provides a unique approach for selectively inhibiting cancer …

Single‐atom nanozymes (SAzymes) have obtained increasing interest to mimic natural
enzymes for efficient cancer therapy, while challenged by chemoresistance from cellular …

Vitiligo, a common skin disease that seriously affects 0.5–2.0% of the worldwide population,
lacks approved therapeutics due to a wide range of adverse side effects. As a key regulator …