Phylogeny to function: PE/PPE protein evolution and impact on Mycobacterium tuberculosis pathogenicity
The pe/ppe genes represent one of the most intriguing aspects of the M ycobacterium
tuberculosis genome. These genes are especially abundant in pathogenic mycobacteria …
tuberculosis genome. These genes are especially abundant in pathogenic mycobacteria …
Mycobacterial PE/PPE proteins at the host‐pathogen interface
SL Sampson - Journal of Immunology Research, 2011 - Wiley Online Library
The mycobacterial PE/PPE proteins have attracted much interest since their formal
identification just over a decade ago. It has been widely speculated that these proteins may …
identification just over a decade ago. It has been widely speculated that these proteins may …
Structural characteristics, binding partners and related diseases of the calponin homology (CH) domain
LM Yin, M Schnoor, CD Jun - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
The calponin homology (CH) domain is one of the most common modules in various actin-
binding proteins and is characterized by an α-helical fold. The CH domain plays important …
binding proteins and is characterized by an α-helical fold. The CH domain plays important …
Mycobacteria and the intraphagosomal environment: take it with a pinch of salt (s)!
Ancient protozoan phagocytes and modern professional phagocytes of metazoans, such as
macrophages, employ evolutionarily conserved mechanisms to kill microbes. These …
macrophages, employ evolutionarily conserved mechanisms to kill microbes. These …
The PE and PPE proteins of Mycobacterium tuberculosis
S Mukhopadhyay, KN Balaji - Tuberculosis, 2011 - Elsevier
India already has earned the dubious distinction of being one of the countries with the
highest incidence of tuberculosis (TB). The conventional control measures have had little …
highest incidence of tuberculosis (TB). The conventional control measures have had little …
Role of the PE/PPE family in host–pathogen interactions and prospects for anti-tuberculosis vaccine and diagnostic tool design
J Qian, R Chen, H Wang, X Zhang - Frontiers in cellular and infection …, 2020 - frontiersin.org
The pe/ppe genes are found in pathogenic, slow-growing Mycobacterium tuberculosis and
other M. tuberculosis complex (MTBC) species. These genes are considered key factors in …
other M. tuberculosis complex (MTBC) species. These genes are considered key factors in …
Responses of Bovine Innate Immunity to Mycobacterium avium subsp. paratuberculosis Infection Revealed by Changes in Gene Expression and Levels of MicroRNA
M Malvisi, F Palazzo, N Morandi, B Lazzari… - PloS one, 2016 - journals.plos.org
Paratuberculosis in cattle is a chronic granulomatous gastroenteritis caused by
Mycobacterium avium subsp. paratubercolosis (MAP) which is endemic worldwide. In dairy …
Mycobacterium avium subsp. paratubercolosis (MAP) which is endemic worldwide. In dairy …
Mycobacterium tuberculosis Co-operonic PE32/PPE65 Proteins Alter Host Immune Responses by Hampering Th1 Response
PE/PPE genes, present in cluster with ESAT-6 like genes, are suspected to have a role in
antigenic variation and virulence of Mycobacterium tuberculosis. Their roles in immune …
antigenic variation and virulence of Mycobacterium tuberculosis. Their roles in immune …
Comparative genomic and proteomic analyses of PE/PPE multigene family of Mycobacterium tuberculosis H37Rv and H37Ra reveal novel and interesting …
Tuberculosis, caused by Mycobacterium tuberculosis, remains a leading infectious disease
taking one human life every 15 s globally. The two well-characterized strains H37Rv and …
taking one human life every 15 s globally. The two well-characterized strains H37Rv and …
PE11 (Rv1169c) selectively alters fatty acid components of Mycobacterium smegmatis and host cell interleukin-6 level accompanied with cell death
W Deng, J Zeng, X **ang, P Li, J **e - Frontiers in microbiology, 2015 - frontiersin.org
PE/PPE family proteins, named after their conserved PE (Pro-Glu) and PPE (Pro-Pro-Glu)
domains of N-terminal, are most intriguing aspects of pathologic mycobacterial genome. The …
domains of N-terminal, are most intriguing aspects of pathologic mycobacterial genome. The …