Risk factors for progression of age‐related macular degeneration

TJ Heesterbeek, L Lorés‐Motta… - Ophthalmic and …, 2020 - Wiley Online Library
Purpose Age‐related macular degeneration (AMD) is a degenerative disease of the macula,
often leading to progressive vision loss. The rate of disease progression can vary among …

A review on mesenchymal stem cells for treatment of retinal diseases

S Adak, D Magdalene, S Deshmukh, D Das… - Stem cell reviews and …, 2021 - Springer
Abstract Mesenchymal Stem Cells (MSCs) have been studied extensively for the treatment
of several retinal diseases. The therapeutic potential of MSCs lies in its ability to differentiate …

[HTML][HTML] Systemic and ocular fluid compounds as potential biomarkers in age-related macular degeneration

E Kersten, CC Paun, RL Schellevis, CB Hoyng… - survey of …, 2018 - Elsevier
Biomarkers can help unravel mechanisms of disease and identify new targets for therapy.
They can also be useful in clinical practice for monitoring disease progression, evaluation of …

Intravitreal administration of multipotent mesenchymal stromal cells triggers a cytoprotective microenvironment in the retina of diabetic mice

M Ezquer, CA Urzua, S Montecino, K Leal… - Stem cell research & …, 2016 - Springer
Background Diabetic retinopathy is a common complication of diabetes and the leading
cause of irreversible vision loss in the Western world. The reduction in color/contrast …

Cellular reparative mechanisms of mesenchymal stem cells for retinal diseases

SLS Ding, S Kumar, PL Mok - International Journal of Molecular Sciences, 2017 - mdpi.com
The use of multipotent mesenchymal stem cells (MSCs) has been reported as promising for
the treatment of numerous degenerative disorders including the eye. In retinal degenerative …

Efficacy and safety of autologous bone marrow mesenchymal stem cell transplantation in patients with diabetic retinopathy

X Gu, X Yu, C Zhao, P Duan, T Zhao, Y Liu… - Cellular Physiology and …, 2018 - karger.com
Abstract Background/Aims: The treatment options for diabetic retinopathy (DR) are limited.
Mesenchymal stem cells (MSCs) are a promising treatment option for diabetes and its …

Polysaccharide hydrogel combined with mesenchymal stem cells promotes the healing of corneal alkali burn in rats

Y Ke, Y Wu, X Cui, X Liu, M Yu, C Yang, X Li - PloS one, 2015 - journals.plos.org
Corneal chemical burns are common ophthalmic injuries that may result in permanent visual
impairment. Although significant advances have been achieved on the treatment of such …

A drug delivery system of HIF-1α siRNA nanoparticles loaded by mesenchymal stem cells on choroidal neovascularization

L Zhang, W Qiang, MQ Li, SJ Wang, W Jia, R Wang… - …, 2024 - Taylor & Francis
Aim: To assess mesenchymal stem cells (MSCs) as carriers for HIF-1α siRNA-loaded
nanoparticles (NPs) for targeted therapy of experimental choroidal neovascularization …

Adult stem cell-based strategies for peripheral nerve regeneration

MB De la Rosa, EM Kozik, DS Sakaguchi - … Volume 4: Stem Cells and Cell …, 2018 - Springer
Peripheral nerve injuries (PNI) occur as the result of sudden trauma and can lead to life-long
disability, reduced quality of life, and heavy economic and social burdens. Although the …

Revisiting the role of erythropoietin for treatment of ocular disorders

SL Shirley Ding, SN Leow, R Munisvaradass, EH Koh… - Eye, 2016 - nature.com
Erythropoietin (EPO) is a glycoprotein hormone conventionally thought to be responsible
only in producing red blood cells in our body. However, with the discovery of the presence of …