The key to regenerative medicine is in situ regeneration of lesion cells, so as to achieve
lesion repair and regeneration. However, the complex environment of the joint cavity where …

There is an increased interest in renewable carbon as a source of materials, where lignin is
expected to play a prominent role. This stems, partially, from new regulations aiming to …

Large bone defects resulting from fractures and disease are a major clinical challenge,
being often unable to heal spontaneously by the body's repair mechanisms. Lines of …

Hydrogel scaffolds are attractive for tissue defect repair and reorganization because of their
human tissue-like characteristics. However, most hydrogels offer limited cell growth and …

Absorbent polymers or hydrogel polymer materials have an enhanced water retention
capacity and are widely used in agriculture and medicine. The controlled release of …

The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Photocrosslinked gelatin methacryloyl (GelMA) hydrogels have attracted great concern in
the biomedical field because of their good biocompatibility and tunable physicochemical …

Despite tremendous advances in the field of regenerative medicine, it still remains
challenging to repair the osteochondral interface and full-thickness articular cartilage …

Additive manufacturing, otherwise known as three-dimensional (3D) printing, is driving
major innovations in many areas, such as engineering, manufacturing, art, education and …

Stable integration of hydrogel implants with host tissues is of critical importance to cartilage
tissue engineering. Designing and fabricating hydrogels with high adhesive strength …