TGF-β plays a prominent role as an inducer of epithelial-mesenchymal transitions (EMTs)
during development and wound healing and in disease conditions such as fibrosis and …

Skeletal muscle is the largest tissue in the body and loss of its function or its regenerative
properties results in debilitating musculoskeletal disorders. Understanding the mechanisms …

Epithelial-to-mesenchymal transitions (EMTs) are phenotypic plasticity processes that confer
migratory and invasive properties to epithelial cells during development, wound-healing …

The mammary gland is a compound, branched tubuloalveolar structure and a major
characteristic of mammals. The mammary gland has evolved from epidermal apocrine …

The transdifferentiation of epithelial cells into motile mesenchymal cells, a process known as
epithelial–mesenchymal transition (EMT), is integral in development, wound healing and …

Epithelial-mesenchymal transition (EMT) is a highly conserved process in which polarized,
immobile epithelial cells lose tight junctions, associated adherence, and become migratory …

The significant parallels between cell plasticity during embryonic development and
carcinoma progression have helped us understand the importance of the epithelial …

The epithelial mesenchymal transition (EMT) plays a central role in both normal
physiological events (eg, embryonic development) and abnormal pathological events (eg …

The minimal structural unit of a solid tumor is a single cell or a cellular compartment such as
the nucleus. A closer look inside the cells reveals that there are functional compartments or …

The origins of the mesenchymal cells participating in tissue repair and pathological
processes, notably tissue fibrosis, tumor invasiveness, and metastasis, are poorly …