The emerging role of Raman spectroscopy as an omics approach for metabolic profiling and biomarker detection toward precision medicine

G Cutshaw, S Uthaman, N Hassan… - Chemical …, 2023 - ACS Publications
Omics technologies have rapidly evolved with the unprecedented potential to shape
precision medicine. Novel omics approaches are imperative toallow rapid and accurate data …

Raman spectroscopy and related techniques in biomedicine

A Downes, A Elfick - Sensors, 2010 - mdpi.com
In this review we describe label-free optical spectroscopy techniques which are able to non-
invasively measure the (bio) chemistry in biological systems. Raman spectroscopy uses …

Raman spectroscopy and imaging in bioanalytics

D Cialla-May, C Krafft, P Rösch… - Analytical …, 2021 - ACS Publications
Since the discovery of the inelastic scattering of light, ie, the so-called Raman effect, 1
Raman spectroscopy has become an attractive tool in a high number of research fields …

Chemically sensitive bioimaging with coherent Raman scattering

CH Camp Jr, MT Cicerone - Nature photonics, 2015 - nature.com
Raman scattering provides an intrinsic fingerprint of chemical composition. Spontaneous
Raman spectroscopy has been used for many decades to interrogate biological materials …

Raman and coherent anti-Stokes Raman scattering microspectroscopy for biomedical applications

C Krafft, B Dietzek, M Schmitt… - Journal of biomedical …, 2012 - spiedigitallibrary.org
A tutorial article is presented for the use of linear and nonlinear Raman microspectroscopies
in biomedical diagnostics. Coherent anti-Stokes Raman scattering (CARS) is the most …

Quantitative coherent anti-Stokes Raman scattering (CARS) microscopy

JPR Day, KF Domke, G Rago, H Kano… - The Journal of …, 2011 - ACS Publications
The ability to observe samples qualitatively at the microscopic scale has greatly enhanced
our understanding of the physical and biological world throughout the 400 year history of …

Coherent stokes Raman scattering microscopy (CSRS)

S Heuke, H Rigneault - Nature Communications, 2023 - nature.com
We report the first implementation of laser scanning coherent Stokes Raman scattering
(CSRS) microscopy. To overcome the major challenge in CSRS imaging, we show how to …

Deep learning as phase retrieval tool for CARS spectra

R Houhou, P Barman, M Schmitt, T Meyer, J Popp… - Optics …, 2020 - opg.optica.org
Finding efficient and reliable methods for the extraction of the phase in optical
measurements is challenging and has been widely investigated. Although sophisticated …

Coherent anti-Stokes Raman spectroscopy of single and multi-layer graphene

A Virga, C Ferrante, G Batignani, D De Fazio… - Nature …, 2019 - nature.com
Spontaneous Raman spectroscopy is a powerful characterization tool for graphene
research. Its extension to the coherent regime, despite the large nonlinear third-order …

Label-free cellular imaging by broadband coherent anti-Stokes Raman scattering microscopy

SH Parekh, YJ Lee, KA Aamer, MT Cicerone - Biophysical journal, 2010 - cell.com
Raman microspectroscopy can provide the chemical contrast needed to characterize the
complex intracellular environment and macromolecular organization in cells without …