The interest in 3, 4-dihydropyrimidine-2 (1 H)-(thio) ones is increasing every day, mainly due
to their paramount biological relevance. The Biginelli reaction is the classical approach to …

This review covers up to 2010 and some available references of 2011 of synthetic advances
in the Biginelli reaction, including recent mechanistic advances, new building blocks, new …

To obtain a multipotent framework that can target simultaneously COX-2, 5-LOX,
acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) to treat neuroinflammation …

Abstract Triazole tethered 7-chloroquinoline-pyrimidine-5-carboxylate hybrids were
synthesized and evaluated for antiplasmodial activity against chloroquine sensitive (CQ S) …

An efficient visible-light-driven photocatalytic oxidation of various 2-substituted
dihydropyrimidines and phenolic imines has been achieved using an organic photocatalyst …

A series of pyrimidine derivatives bearing amine substituents at C-2 position were obtained
from Biginelli 3, 4-dihydropyrimidin-2 (1H)-ones and the effect of structural variation on anti …

2-Aminopyrimidine based 4-aminoquinolines were synthesized using an efficacious
protocol. Some of the compounds showed in vitro anti-plasmodial activity against drug …

A pyrene-based small molecular weight probe, exhibiting aggregation enhanced excimer
emission has been synthesized. The crystalline emissive form detects 2, 4, 6-trinitrophenol …

The syntheses and investigations of new biologically active derivatives of
dihydropyrimidines by Biginelli reaction in the presence of copper triflate are reported. Due …

The promise of hybrid antimalarial agents and the precedence set by the antimalarial drug
ferroquine prompted us to design ferrocene-pyrimidine conjugates. Herein, we report the …