The high mobility group protein 2 (HMGA2) regulates gene expression by binding to AT-rich
regions of DNA. Akin to other DNA architectural proteins, HMGA2 is highly expressed in …

Human papilloma viruses (HPV) are a small group of non-enveloped viruses belonging to
the Papillomaviridae family with strong similarities to polyoma viruses. The viral particles …

Cervical cancer is a common gynecological malignancy often caused by high-risk human
papillomavirus. There is a paucity of human-derived culture systems to study the cervical …

Patients with human papillomavirus (HPV+)–associated head and neck cancer (HNC) show
significantly improved survival outcome compared with those with HPV-negative (HPV−) …

Many econometric and data-science applications require a reliable estimate of the
covariance matrix, such as Markowitz's portfolio selection. When the number of variables is …

The chemokine interferon-γ inducible protein 10 kDa (CXCL10) is a member of the CXC
chemokine family which binds to the CXCR3 receptor to exert its biological effects. CXCL10 …

To study the multistep process of cervical cancer development, we analyzed 128 frozen
cervical samples spanning normalcy, increasingly severe cervical intraepithelial neoplasia …

Background: There is a need to develop robust and clinically applicable gene expression
signatures. Hypoxia is a key factor promoting solid tumour progression and resistance to …

Background: We aimed to investigate the prognostic value of tumour-infiltrating
lymphocytes'(TILs) expression in pretreatment specimens from patients with head and neck …

Abstract Viruses cause 10–15% of all human cancers. Massively parallel sequencing has
recently proved effective for uncovering novel viruses and virus–tumour associations, but …