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Abnormal function of telomere protein TRF2 induces cell mutation and the effects of environmental tumor-promoting factors
Z Wang, X Wu - Oncology reports, 2021 - spandidos-publications.com
Recent studies have found that somatic gene mutations and environmental tumor-promoting
factors are both indispensable for tumor formation. Telomeric repeat-binding factor (TRF) 2 …
factors are both indispensable for tumor formation. Telomeric repeat-binding factor (TRF) 2 …
[HTML][HTML] Telomere Length and Telomerase Activity as Potential Biomarkers for Gastrointestinal Cancer
Simple Summary Cancer affects millions worldwide, with gastrointestinal cancers being
notably common. This review explores the potential of telomeres and telomerase as …
notably common. This review explores the potential of telomeres and telomerase as …
Prognostic role of telomere length in malignancies: A meta-analysis and meta-regression
R Adam, L Diez-Gonzalez, A Ocana, B Šeruga… - … and molecular pathology, 2017 - Elsevier
Telomere length (TL) has been associated with several health conditions including cancer.
To quantify the effect of TL on outcomes in malignancies and explore the role of type of TL …
To quantify the effect of TL on outcomes in malignancies and explore the role of type of TL …
Telomere length is correlated with mitochondrial DNA copy number in intestinal, but not diffuse, gastric cancer
SJ Jung, JH Cho, WJ Park, YR Heo… - Oncology …, 2017 - spandidos-publications.com
A positive correlation between telomere length and mitochondrial DNA (mtDNA) copy
number has previously been observed in healthy individuals, and in patients with psychiatric …
number has previously been observed in healthy individuals, and in patients with psychiatric …
Telomere and telomerase in carcinogenesis: their role as prognostic biomarkers
S Giunco, E Rampazzo, A Celeghin, MR Petrara… - Current Pathobiology …, 2015 - Springer
Unlimited replicative potential is the hallmark of cancer cells. Telomere shortening, which
occurs at each cell division, restricts cell proliferation in normal somatic cells. Maintenance …
occurs at each cell division, restricts cell proliferation in normal somatic cells. Maintenance …
Telomere DNA damage signaling regulates cancer stem cell evolution, epithelial mesenchymal transition, and metastasis
AM Lagunas, J Wu, DL Crowe - Oncotarget, 2017 - pmc.ncbi.nlm.nih.gov
Chromosome ends are protected by telomeres that prevent DNA damage response and
degradation. When telomeres become critically short, the DNA damage response is …
degradation. When telomeres become critically short, the DNA damage response is …
[PDF][PDF] TERT promoter mutation, telomere length, and TERT expression in gastric cancer
H Lee, JD **, BM La, WJ Park, IJ Choi, JH Lee - 2016 - kumel.medlib.dsmc.or.kr
Objective: The mutation in the promoter region of telomerase reverse transcriptase (TERT)
has been focused in various cancers. In present study, the frequency and clinical …
has been focused in various cancers. In present study, the frequency and clinical …
[PDF][PDF] Studies on the mutagenic and tumor-promoting effects of TRF2 protein in the mechanism of tumor formation
Z Wang, L Zhou, X Wu - J Clin Images Med Case Rep, 2023 - jcimcr.org
In recent years, the gene mutation hypothesis related to tumor formation has been deeply
studied, and some scholars have put forward some new views on the basis of the original …
studied, and some scholars have put forward some new views on the basis of the original …
[PDF][PDF] FACULTAD DE INFORMÁTICA
AI Martínez - 2022 - core.ac.uk
Applications of Information Theory and Artificial Intelligence to Software Testing Page 1
UNIVERSIDAD COMPLUTENSE DE MADRID FACULTAD DE INFORMÁTICA TESIS …
UNIVERSIDAD COMPLUTENSE DE MADRID FACULTAD DE INFORMÁTICA TESIS …
Análisis de parámetros de función telomérica en tejidos tumorales y adiposos de pacientes afectados de Cáncer Colorrectal: relación con obesidad
S García Martínez - 2023 - docta.ucm.es
Los telómeros son complejos nucleoproteicos que protegen los extremos de los
cromosomas lineales de las células eucariotas. Esto se consigue a través de la formación …
cromosomas lineales de las células eucariotas. Esto se consigue a través de la formación …