Unlocking the full potential of SGLT2 inhibitors: expanding applications beyond glycemic control

ME Youssef, G Yahya, MS Popoviciu, S Cavalu… - International Journal of …, 2023‏ - mdpi.com
The number of diabetic patients has risen dramatically in recent decades, owing mostly to
the rising incidence of type 2 diabetes mellitus (T2DM). Several oral antidiabetic …

[HTML][HTML] The role of bone-derived hormones in glucose metabolism, diabetic kidney disease, and cardiovascular disorders

Y Takashi, D Kawanami - International Journal of Molecular Sciences, 2022‏ - mdpi.com
Bone contributes to supporting the body, protecting the central nervous system and other
organs, hematopoiesis, the regulation of mineral metabolism (mainly calcium and …

[HTML][HTML] A review of current evidence on the relationship between phosphate metabolism and metabolic syndrome

SK Wong - Nutrients, 2022‏ - mdpi.com
Phosphorus, present as phosphate in biological systems, is an essential mineral for various
biological activities and biochemical processes. Numerous studies have indicated that …

Interrelationships among metabolic syndrome, bone-derived cytokines, and the most common metabolic syndrome-related diseases negatively affecting bone quality

M Martiniakova, V Mondockova, V Kovacova… - Diabetology & Metabolic …, 2024‏ - Springer
Metabolic syndrome (MetS), as a set of medical conditions including hyperglycemia,
hypertension, abdominal obesity, and dyslipidemia, represents a highly prevalent disease …

Advances in FGFs for diabetes care applications

Y Liu, Q Chen, Y Li, L Bi, Z He, C Shao, L **, R Peng… - Life Sciences, 2022‏ - Elsevier
Background Diabetes mellitus (DM) is an endocrine and metabolic disease caused by a
variety of pathogenic factors, including genetic factors, environmental factors and behavior …

The emerging role of bone-derived hormones in diabetes mellitus and diabetic kidney disease

Y Li, Z Gu, J Wang, Y Wang, X Chen… - Frontiers in …, 2022‏ - frontiersin.org
Diabetic kidney disease (DKD) causes the greatest proportion of end-stage renal disease
(ESRD)–related mortality and has become a high concern in patients with diabetes mellitus …

Severe 25-hydroxyvitamin D deficiency may predict poor renal outcomes in patients with biopsy-proven diabetic nephropathy

T Zhou, L Shen, Z Li, J Jia, H **ng, N Wang… - Frontiers in …, 2022‏ - frontiersin.org
Aims This study aims to investigate the role of 25-hydroxyvitamin D (25 (OH) D) levels in
predicting renal survival in biopsy-proven diabetic nephropathy (DN) with type 2 diabetes …

Calcium-phosphate homeostasis and insulin resistance in men

V Carnevale, L Nieddu, A Scillitani, MG Tinti… - Nutrition, Metabolism …, 2024‏ - Elsevier
Background and aims Data on P homeostasis in insulin resistance (IR) are still conflicting.
We investigated calcium-phosphate homeostasis parameters in men with/without IR …

Serum fibroblast growth factor 23 levels are associated with vascular smooth muscle dysfunction in type 2 diabetes

Y Natsuki, T Morioka, Y Kakutani… - … of Atherosclerosis and …, 2023‏ - jstage.jst.go.jp
Aim: Increased level of serum fibroblast growth factor 23 (FGF23) is a hallmark of abnormal
phosphate metabolism in patients with chronic kidney disease (CKD) and is recently shown …

[HTML][HTML] Phosphocalcic metabolism and its potential association with biomarkers of kidney disease in dogs with spontaneous hyperadrenocorticism

F Da Riz, D Pichard, C Maurey, M Kurtz… - The Veterinary …, 2024‏ - Elsevier
The pathogenesis of increased serum phosphate concentration and proteinuria in dogs with
spontaneous hyperadrenocorticism (HAC) is unclear. A potential link between proteinuria …