It is now well established that mature spermatozoa harbour a rich and diverse profile of
small non-protein-coding regulatory RNAs (sRNAs). There is also growing appreciation that …

The ongoing Zika virus epidemic in the Americas and the observed association with both
fetal abnormalities (primary microcephaly) and adult autoimmune pathology (Guillain–Barré …

Background Our understanding of epididymal physiology and function has been
transformed over the three decades in which the International Meeting Series on the …

Thioredoxin/glutathione reductase (TXNRD3) is a selenoprotein composed of thioredoxin
reductase and glutaredoxin domains. This NADPH-dependent thiol oxidoreductase evolved …

Spermatogenesis is one of the fundamental processes of sexual reproduction, present in
almost all metazoan animals. Like many other reproductive traits, developmental features …

The Musashi family of mRNA translational regulators controls both physiological and
pathological stem cell self-renewal primarily by repressing target mRNAs that promote …

Spermatogenesis requires a large number of proteins to be properly expressed at certain
stages, during which post-transcriptional regulation plays an important role. RNA-binding …

The Musashi family of RNA-binding proteins is known for its role in stem-cell renewal and is
a negative regulator of cell differentiation. Interestingly, in the retina, the Musashi proteins …

Objectives RNA‐binding proteins (RBPs) play essential post‐transcriptional roles in
regulating spermatogonial stem cells (SSCs) maintenance and differentiation. We identified …

A number of mutations in genes that encode ubiquitously expressed RNA-binding proteins
cause tissue specific disease. Many of these diseases are neurological in nature revealing …