Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …

The new coronavirus disease-2019 (COVID-19), which is spreading around the world and
threatening people, is easily infecting a large number of people through airborne droplets; …

In atherosclerosis patients, vascular endothelial dysfunction is commonly observed
alongside damage of the vascular endothelial glycocalyx, an extracellular matrix bound to …

Heparan sulfate proteoglycans (HSPGs) encompass a group of glycoproteins composed of
unbranched negatively charged heparan sulfate (HS) chains covalently attached to a core …

Abstracts Background The number of studies measuring breakdown products of the
glycocalyx in plasma has increased rapidly during the past decade. The purpose of the …

The classic Starling principle proposed that microvascular fluid exchange was determined
by a balance of hydrostatic and oncotic pressures relative to the vascular wall and this …

The physiological, anti-inflammatory, and anti-coagulant properties of endothelial cells
(ECs) rely on a complex carbohydrate-rich layer covering the luminal surface of ECs, called …

In the 1900s, researchers established animal models experimentally to induce
atherosclerosis by feeding them with a cholesterol-rich diet. It is now accepted that high …

The accumulation of low-density lipoproteins (LDL) in the arterial wall plays a pivotal role in
the initiation and pathogenesis of atherosclerosis. Conversely, the removal of cholesterol …

Background Disruption of the endothelial glycocalyx contributes to acute lung injury in
experimental sepsis but has not been well studied in humans. To study glycocalyx …