The protein corona from nanomedicine to environmental science

M Mahmoudi, MP Landry, A Moore… - Nature Reviews Materials, 2023 - nature.com
The protein corona spontaneously develops and evolves on the surface of nanoscale
materials when they are exposed to biological environments, altering their physiochemical …

Nanoparticle–cell interactions: molecular structure of the protein corona and cellular outcomes

CC Fleischer, CK Payne - Accounts of chemical research, 2014 - ACS Publications
Conspectus The use of nanoparticles (NPs) in biology and medicine requires a molecular-
level understanding of how NPs interact with cells in a physiological environment. A critical …

Modeling and simulation of protein–surface interactions: achievements and challenges

M Ozboyaci, DB Kokh, S Corni… - Quarterly reviews of …, 2016 - cambridge.org
Understanding protein–inorganic surface interactions is central to the rational design of new
tools in biomaterial sciences, nanobiotechnology and nanomedicine. Although a significant …

Mass spectrometry-based top-down proteomics in nanomedicine: proteoform-specific measurement of protein corona

SA Sadeghi, AA Ashkarran, Q Wang, G Zhu… - ACS …, 2024 - ACS Publications
Conventional mass spectrometry (MS)-based bottom-up proteomics (BUP) analysis of the
protein corona [ie, an evolving layer of biomolecules, mostly proteins, formed on the surface …

ATR-FTIR spectroscopy as a tool to probe surface adsorption on nanoparticles at the liquid–solid interface in environmentally and biologically relevant media

IA Mudunkotuwa, A Al Minshid, VH Grassian - Analyst, 2014 - pubs.rsc.org
Given the importance of nanoparticle surface composition in nanotoxicology, analytical tools
that can probe nanoparticle surfaces in aqueous media are crucial but remain limited …

Adsorption and unfolding of a single protein triggers nanoparticle aggregation

S Dominguez-Medina, L Kisley, LJ Tauzin, A Hoggard… - ACS …, 2016 - ACS Publications
The response of living systems to nanoparticles is thought to depend on the protein corona,
which forms shortly after exposure to physiological fluids and which is linked to a wide array …

Secondary structure of corona proteins determines the cell surface receptors used by nanoparticles

CC Fleischer, CK Payne - The Journal of Physical Chemistry B, 2014 - ACS Publications
Nanoparticles used for biological and biomedical applications encounter a host of
extracellular proteins. These proteins rapidly adsorb onto the nanoparticle surface, creating …

Understanding the fate and biological effects of Ag-and TiO2-nanoparticles in the environment: the quest for advanced analytics and interdisciplinary concepts

GE Schaumann, A Philippe, M Bundschuh… - Science of the Total …, 2015 - Elsevier
Engineered inorganic nanoparticles (EINP) from consumers' products and industrial
applications, especially silver and titanium dioxide nanoparticles (NP), are emitted into the …

[HTML][HTML] Nanoparticle and nanomineral production by fungi

Q Li, F Liu, M Li, C Chen, GM Gadd - Fungal Biology Reviews, 2022 - Elsevier
Fungi show a variety of abilities in affecting metal speciation, toxicity, and mobility and
mineral formation, dissolution or deterioration through several interacting biomechanical …

Adsorption of a protein monolayer via hydrophobic interactions prevents nanoparticle aggregation under harsh environmental conditions

S Dominguez-Medina, J Blankenburg… - ACS sustainable …, 2013 - ACS Publications
We find that citrate-stabilized gold nanoparticles aggregate and precipitate in saline
solutions below the NaCl concentration of many bodily fluids and blood plasma. Our …