Designing bioresponsive nanomaterials for intracellular self-assembly

S Chagri, DYW Ng, T Weil - Nature Reviews Chemistry, 2022 - nature.com
Supramolecular assemblies are essential components of living organisms. Cellular
scaffolds, such as the cytoskeleton or the cell membrane, are formed via secondary …

The in vivo fate of polymeric micelles

Y Cai, J Qi, Y Lu, H He, W Wu - Advanced Drug Delivery Reviews, 2022 - Elsevier
This review aims to provide a systemic analysis of the in vivo, as well as subcellular, fate of
polymeric micelles (PMs), starting from the entry of PMs into the body. Few PMs are able to …

Aggregation-induced emission: a trailblazing journey to the field of biomedicine

C Zhu, RTK Kwok, JWY Lam… - ACS Applied Bio Materials, 2018 - ACS Publications
The emergence of the aggregation-induced emission (AIE) concept significantly changes
the cognition of the scientific community toward classic photophysical phenomena. More …

Aggregation-induced emission

Y Hong, JWY Lam, BZ Tang - Chemical Society Reviews, 2011 - pubs.rsc.org
Luminogenic materials with aggregation-induced emission (AIE) attributes have attracted
much interest since the debut of the AIE concept in 2001. In this critical review, recent …

Polymeric AIE-based nanoprobes for biomedical applications: recent advances and perspectives

X Zhang, K Wang, M Liu, X Zhang, L Tao, Y Chen… - Nanoscale, 2015 - pubs.rsc.org
The development of polymeric luminescent nanomaterials for biomedical applications has
recently attracted a large amount of attention due to the remarkable advantages of these …

New sensing mechanisms for design of fluorescent chemosensors emerging in recent years

J Wu, W Liu, J Ge, H Zhang, P Wang - Chemical Society Reviews, 2011 - pubs.rsc.org
During the past decade, fluorescent chemosensors have become an important research
field of supramolecular chemistry and have attracted great attention because of their …

Chromogenic/fluorogenic ensemble chemosensing systems

J Wu, B Kwon, W Liu, EV Anslyn, P Wang… - Chemical …, 2015 - ACS Publications
Nature has endowed human beings with many useful functions, by virtue of supramolecular
chemistry. As is well-known, nature can self-assemble relatively small molecular precursors …

Aggregation-induced emission: phenomenon, mechanism and applications

Y Hong, JWY Lam, BZ Tang - Chemical communications, 2009 - pubs.rsc.org
It is textbook knowledge that chromophore aggregation generally quenches light emission.
In this feature article, we give an account on how we observed an opposite phenomenon …

Real-time monitoring of cell apoptosis and drug screening using fluorescent light-up probe with aggregation-induced emission characteristics

H Shi, RTK Kwok, J Liu, B **ng… - Journal of the American …, 2012 - ACS Publications
Real-time monitoring of cell apoptosis could provide valuable insights into early detection of
therapy efficiency and evaluation of disease progression. In this work, we designed and …

Acetylenic polymers: syntheses, structures, and functions

J Liu, JWY Lam, BZ Tang - Chemical reviews, 2009 - ACS Publications
The synthesis of polymers is of academic value and technological implication and has been
developed as an important area of research over a long history. 1 The first reports about …