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Crosstalk mechanisms between glomerular endothelial cells and podocytes in renal diseases and kidney transplantation
The glomerular filtration barrier (GFB), composed of endothelial cells, glomerular basement
membrane, and podocytes, is a unique structure for filtering blood while detaining plasma …
membrane, and podocytes, is a unique structure for filtering blood while detaining plasma …
An interleukin 6‐based genetic risk score strengthened with interleukin 10 polymorphisms associated with long‐term kidney allograft outcomes
Of all kidney transplants, half are still lost in the first decade after transplantation. Here, using
genetics, we probed whether interleukin 6 (IL‐6) could be a target in kidney transplantation …
genetics, we probed whether interleukin 6 (IL‐6) could be a target in kidney transplantation …
Donor genetic burden for cerebrovascular risk and kidney transplant outcome
Background and hypothesis Kidney grafts from donors who died of stroke and related traits
have worse outcomes relative to grafts from both living donors and those who died of other …
have worse outcomes relative to grafts from both living donors and those who died of other …
Association between pre-transplant oral health and post-liver transplant complications
AE Olander, J Helenius-Hietala… - Transplant …, 2023 - frontierspartnerships.org
Oral disease is linked with systemic inflammation and various systemic conditions, including
chronic liver disease. Liver transplantation (LT) candidates often need dental infection focus …
chronic liver disease. Liver transplantation (LT) candidates often need dental infection focus …
A functional TGFB1 polymorphism in the donor associates with long-term graft survival after kidney transplantation
Background Improvement of long-term outcomes in kidney transplantation remains one of
the most pressing challenges, yet drug development is stagnating. Human genetics offers an …
the most pressing challenges, yet drug development is stagnating. Human genetics offers an …
Carboxypeptidase B2 gene polymorphisms in the donor associate with kidney allograft loss
Abstract Introduction Plasma carboxypeptidase B2 (CPB2) is an enzyme that cleaves C-
terminal amino acids from proteins, thereby regulating their activities. CPB2 has anti …
terminal amino acids from proteins, thereby regulating their activities. CPB2 has anti …
Tumor necrosis factor-α gene polymorphism is associated with short-and long-term kidney allograft outcomes
Introduction Kidney transplantation has excellent short-term results with current
immunosuppression regimes, but long-term outcomes have barely improved over the past …
immunosuppression regimes, but long-term outcomes have barely improved over the past …
A non-muscle myosin heavy chain 9 genetic variant is associated with graft failure following kidney transplantation
Background Despite current matching efforts to identify optimal donor-recipient pairs for
kidney transplantation, alloimmunity remains a major source of late transplant failure …
kidney transplantation, alloimmunity remains a major source of late transplant failure …
Synergistic impact of three complement polymorphisms in the donor, not the recipient, on long-term kidney allograft survival
Background Genetic analysis in transplantation offers potential for personalized medicine.
Given the crucial role of the complement system in renal allograft injury, we investigated in …
Given the crucial role of the complement system in renal allograft injury, we investigated in …
Donor genetic burden for cerebrovascular risk and kidney transplant
Background and hypothesis: Kidney grafts from donors who died of stroke and related traits
have worse outcomes relative to grafts from both living donors and those who died of other …
have worse outcomes relative to grafts from both living donors and those who died of other …