Peptidomics

R Hellinger, A Sigurdsson, W Wu… - Nature Reviews …, 2023 - nature.com
Peptides are biopolymers, typically consisting of 2–50 amino acids. They are biologically
produced by the cellular ribosomal machinery or by non-ribosomal enzymes and …

Recent advances in mass spectrometry analysis of neuropeptides

A Phetsanthad, NQ Vu, Q Yu… - Mass spectrometry …, 2023 - Wiley Online Library
Due to their involvement in numerous biochemical pathways, neuropeptides have been the
focus of many recent research studies. Unfortunately, classic analytical methods, such as …

Profiling 26,000 Aplysia californica neurons by single cell mass spectrometry reveals neuronal populations with distinct neuropeptide profiles

PC Chan-Andersen, EV Romanova… - Journal of Biological …, 2022 - Elsevier
Neuropeptides are a chemically diverse class of cell-to-cell signaling molecules that are
widely expressed throughout the central nervous system, often in a cell-specific manner …

Neuropeptidomics: improvements in mass spectrometry imaging analysis and recent advancements

NQ Vu, K DeLaney, L Li - Current Protein and Peptide Science, 2021 - ingentaconnect.com
Neuropeptides are an important class of endogenous peptides in the nervous system that
regulate physiological functions such as feeding, glucose homeostasis, pain, memory …

An Updated Guide to the Identification, Quantitation, and Imaging of the Crustacean Neuropeptidome

W Wu, L Fields, K DeLaney, AR Buchberger… - Peptidomics: Methods and …, 2024 - Springer
Crustaceans serve as a useful, simplified model for studying peptides and neuromodulation,
as they contain numerous neuropeptide homologs to mammals and enable …

Advances in high‐resolution maldi mass spectrometry for neurobiology

K DeLaney, A Phetsanthad, L Li - Mass spectrometry reviews, 2022 - Wiley Online Library
Research in the field of neurobiology and neurochemistry has seen a rapid expansion in the
last several years due to advances in technologies and instrumentation, facilitating the …

Develo** mass spectrometry for the quantitative analysis of neuropeptides

CS Sauer, A Phetsanthad, OL Riusech… - Expert review of …, 2021 - Taylor & Francis
Introduction Neuropeptides are signaling molecules originating in the neuroendocrine
system that can act as neurotransmitters and hormones in many biochemical processes …

Temporal study of the perturbation of crustacean neuropeptides due to severe hypoxia using 4-plex reductive dimethylation

AR Buchberger, CS Sauer, NQ Vu… - Journal of proteome …, 2020 - ACS Publications
Hypoxia (ie, low oxygen (O2) levels) is a common environmental challenge for several
aquatic species, including fish and invertebrates. To survive or escape these conditions …

Mass spectrometry profiling and quantitation of changes in circulating hormones secreted over time in Cancer borealis hemolymph due to feeding behavior

K DeLaney, M Hu, W Wu, MP Nusbaum, L Li - Analytical and bioanalytical …, 2022 - Springer
The crustacean stomatogastric ganglion (STG) is a valuable model for understanding circuit
dynamics in neuroscience as it contains a small number of neurons, all easily …

Roles of eyestalk in salinity acclimatization of mud crab (Scylla paramamosain) by transcriptomic analysis

N Mo, S Shao, Z Cui, C Bao - … and Physiology Part D: Genomics and …, 2024 - Elsevier
Salinity acclimatization refers to the physiological and behavioral adjustments made by
crustaceans to adapt to varying salinity environments. The eyestalk, a neuroendocrine organ …