The epidermal growth factor receptor (EGFR) belongs to the ERBB family of tyrosine kinase
receptors. EGFR signaling cascade is a key regulator in cell proliferation, differentiation …

The task of predicting the interactions between drugs and targets plays a key role in the
process of drug discovery. There is a need to develop novel and efficient prediction …

Proteomics involves the applications of technologies for the identification and quantification
of overall proteins present content of a cell, tissue or an organism. It supplements the other …

Networks are one of the most common ways to represent biological systems as complex sets
of binary interactions or relations between different bioentities. In this article, we discuss the …

Although the genes essential for life have been identified in less complex model organisms,
their elucidation in human cells has been hindered by technical barriers. We used extensive …

Protein‐protein interaction plays key role in predicting the protein function of target protein
and drug ability of molecules. The majority of genes and proteins realize resulting …

We report proteogenomic analysis of diffuse gastric cancers (GCs) in young populations.
Phosphoproteome data elucidated signaling pathways associated with somatic mutations …

Understanding the consequences of regulatory variation in the human genome remains a
major challenge, with important implications for understanding gene regulation and …

Functional partnerships between proteins are at the core of complex cellular phenotypes,
and the networks formed by interacting proteins provide researchers with crucial scaffolds …

Abstract The Pathway Interaction Database (PID, http://pid. nci. nih. gov) is a freely available
collection of curated and peer-reviewed pathways composed of human molecular signaling …