Nanopore sensing is attracting the attention of a large and varied scientific community. One
of the main issues in nanopore sensing is how to associate the measured current signals to …

We study the rate dependent response of a bistable chain subjected to thermal fluctuations.
The study is motivated by the fact that the behavior of this model system is prototypical to a …

Several experimental methods are usually applied for stretching single molecules and
provide valuable insights about the static and dynamic responses induced by externally …

We investigate the behavior of a chain of bistable units with an heterogeneous distribution of
energy jumps between the folded and unfolded states. For homogeneous chains, loaded by …

Single-molecule force spectroscopy techniques allow for the measurement of several static
and dynamic features of macromolecules of biological origin. In particular, atomic force …

We analyze the translocation of a charged particle across an α-Hemolysin (αHL) pore in the
framework of a driven diffusion over an extended energy barrier generated by the electrical …

A theoretical framework capable of predicting the first unit that unfolds in pulled modular
proteins has been recently introduced, for “fast enough” pulling velocities. Within this picture …

We analyse the unfolding pathway of biomolecules comprising several independent
modules in pulling experiments. In a recently proposed model, a critical velocity v_ c has …