The therapeutic potential of psilocybin

H Lowe, N Toyang, B Steele, H Valentine, J Grant, A Ali… - Molecules, 2021 - mdpi.com
The psychedelic effects of some plants and fungi have been known and deliberately
exploited by humans for thousands of years. Fungi, particularly mushrooms, are the principal …

[HTML][HTML] REBUS and the anarchic brain: toward a unified model of the brain action of psychedelics

RL Carhart-Harris, KJ Friston - Pharmacological reviews, 2019 - Elsevier
This paper formulates the action of psychedelics by integrating the free-energy principle and
entropic brain hypothesis. We call this formulation relaxed beliefs under psychedelics …

Microdosing with psilocybin mushrooms: a double-blind placebo-controlled study

F Cavanna, S Muller, LA de la Fuente… - Translational …, 2022 - nature.com
The use of low sub-perceptual doses of psychedelics (“microdosing”) has gained popularity
in recent years. Although anecdotal reports claim multiple benefits associated with this …

Models of psychedelic drug action: modulation of cortical-subcortical circuits

MK Doss, MB Madden, A Gaddis, MB Nebel… - Brain, 2022 - academic.oup.com
Classic psychedelic drugs such as psilocybin and lysergic acid diethylamide (LSD) have
recaptured the imagination of both science and popular culture, and may have efficacy in …

Psychedelics

DE Nichols - Pharmacological reviews, 2016 - Elsevier
Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter
perception and mood and affect numerous cognitive processes. They are generally …

[HTML][HTML] Psychiatry & the psychedelic drugs. Past, present & future

JJH Rucker, J Iliff, DJ Nutt - Neuropharmacology, 2018 - Elsevier
The classical psychedelic drugs, including psilocybin, lysergic acid diethylamide and
mescaline, were used extensively in psychiatry before they were placed in Schedule I of the …

[HTML][HTML] The abuse potential of medical psilocybin according to the 8 factors of the Controlled Substances Act

MW Johnson, RR Griffiths, PS Hendricks… - …, 2018 - Elsevier
This review assesses the abuse potential of medically-administered psilocybin, following the
structure of the 8 factors of the US Controlled Substances Act (CSA). Research suggests the …

Psychedelics, meditation, and self-consciousness

R Millière, RL Carhart-Harris, L Roseman… - Frontiers in …, 2018 - frontiersin.org
In recent years, the scientific study of meditation and psychedelic drugs has seen
remarkable developments. The increased focus on meditation in cognitive neuroscience has …

[HTML][HTML] Psilocybin acutely alters the functional connectivity of the claustrum with brain networks that support perception, memory, and attention

FS Barrett, SR Krimmel, RR Griffiths, DA Seminowicz… - Neuroimage, 2020 - Elsevier
Psychedelic drugs, including the serotonin 2a (5-HT 2A) receptor partial agonist psilocybin,
are receiving renewed attention for their possible efficacy in treating a variety of …

The paradoxical psychological effects of lysergic acid diethylamide (LSD)

RL Carhart-Harris, M Kaelen, M Bolstridge… - Psychological …, 2016 - cambridge.org
Background Lysergic acid diethylamide (LSD) is a potent serotonergic hallucinogen or
psychedelic that modulates consciousness in a marked and novel way. This study sought to …