Human endogenous retrovirus-K (HML-2): a comprehensive review
The human genome contains a large number of retroviral elements acquired over the
process of evolution, some of which are specific to primates. However, as many of these are …
process of evolution, some of which are specific to primates. However, as many of these are …
Human endogenous retrovirus K (HML-2) in health and disease
Human endogenous retroviruses (HERVs) are derived from exogenous retrovirus infections
in the evolution of primates and account for about 8% of the human genome. They were …
in the evolution of primates and account for about 8% of the human genome. They were …
HIV-1 infection activates endogenous retroviral promoters regulating antiviral gene expression
S Srinivasachar Badarinarayan… - Nucleic Acids …, 2020 - academic.oup.com
Although endogenous retroviruses (ERVs) are known to harbor cis-regulatory elements,
their role in modulating cellular immune responses remains poorly understood. Using an …
their role in modulating cellular immune responses remains poorly understood. Using an …
HERV-K (HML-2), the best preserved family of HERVs: endogenization, expression, and implications in health and disease
O Hohn, K Hanke, N Bannert - Frontiers in oncology, 2013 - frontiersin.org
Retroviruses that have the ability to infect germ line cells can become an integral and
inherited part of the host genome. About 8% of the human chromosomal DNA consists of …
inherited part of the host genome. About 8% of the human chromosomal DNA consists of …
HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotency
Background Certain post-translational modifications to histones, including H3K4me3, as
well as binding sites for the transcription factor STAT1, predict the site of integration of …
well as binding sites for the transcription factor STAT1, predict the site of integration of …
Endogenous retrovirus-K promoter: a landing strip for inflammatory transcription factors?
M Manghera, RN Douville - Retrovirology, 2013 - Springer
Humans are symbiotic organisms; our genome is populated with a substantial number of
endogenous retroviruses (ERVs), some remarkably intact, while others are remnants of their …
endogenous retroviruses (ERVs), some remarkably intact, while others are remnants of their …
HIV infection and HERV expression: a review
AC van der Kuyl - Retrovirology, 2012 - Springer
The human genome contains multiple copies of retrovirus genomes known as endogenous
retroviruses (ERVs) that have entered the germ-line at some point in evolution. Several of …
retroviruses (ERVs) that have entered the germ-line at some point in evolution. Several of …
Human endogenous retroviruses and exogenous viral infections
C Bao, Q Gao, H **ang, Y Shen, Q Chen… - Frontiers in Cellular …, 2024 - frontiersin.org
The human genome harbors many endogenous retroviral elements, known as human
endogenous retroviruses (HERVs), which have been integrated into the genome during …
endogenous retroviruses (HERVs), which have been integrated into the genome during …
A HML6 endogenous retrovirus on chromosome 3 is upregulated in amyotrophic lateral sclerosis motor cortex
There is increasing evidence that endogenous retroviruses (ERVs) play a significant role in
central nervous system diseases, including amyotrophic lateral sclerosis (ALS). Studies of …
central nervous system diseases, including amyotrophic lateral sclerosis (ALS). Studies of …
HIV-1 Infection Leads to Increased Transcription of Human Endogenous Retrovirus HERV-K (HML-2) Proviruses In Vivo but Not to Increased Virion Production
N Bhardwaj, F Maldarelli, J Mellors, JM Coffin - Journal of virology, 2014 - Am Soc Microbiol
Recent studies suggest that human endogenous retrovirus group K (HERV-K) provirus
expression plays a role in the pathogenesis of HIV-1 infection. In particular, RNA from the …
expression plays a role in the pathogenesis of HIV-1 infection. In particular, RNA from the …