The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …

Inflammatory bowel diseases (IBDs) are a group of chronic gastrointestinal inflammatory
diseases with unknown etiology. There is a combination of well documented factors in their …

In animal species, the brain–gut axis is a complex bidirectional network between the
gastrointestinal (GI) tract and the central nervous system (CNS) consisting of numerous …

INTRODUCTION An intricate balance with our intestinal microbes is pivotal to human health.
A key interface of host-microbial interactions occurs in the mucus that covers the intestinal …

Throughout the gastrointestinal (GI) tract, a distinct mucus layer composed of highly
glycosylated proteins called mucins plays an essential role in providing lubrication for the …

Simple Summary The gastrointestinal tract is a complex organization of various types of
epithelial cells forming a single layer of the mucosal barrier, the host mucosal immune …

The revolution in microbiota research over the past decade has provided invaluable
knowledge about the function of the microbial species that inhabit the human body. It has …

Diverse microbial signatures within the intestinal microbiota have been associated with
intestinal and systemic inflammatory diseases, but whether these candidate microbes …

The human gastrointestinal tract is colonized by trillions of microorganisms that interact with
the host to maintain structural and functional homeostasis. Acting as the interface between …

The intestinal tract of mammals is colonized by a large number of microorganisms including
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …