The evolution of microfluidic‐based drug‐loading techniques for cells and their derivatives

S Tong, J Niu, Z Wang, Y Jiao, Y Fu, D Li, X Pan… - Small, 2024 - Wiley Online Library
Conventional drug delivery techniques face challenges related to targeting and adverse
reactions. Recent years have witnessed significant advancements in nanoparticle‐based …

Automating CAR‐T transfection with micro and nano‐technologies

T Hu, ARK Kumar, Y Luo, A Tay - Small Methods, 2024 - Wiley Online Library
Cancer poses a significant health challenge, with traditional treatments like surgery,
radiotherapy, and chemotherapy often lacking in cell specificity and long‐term curative …

Non-viral delivery of RNA for therapeutic T cell engineering

D Berdecka, SC De Smedt, WH De Vos… - Advanced Drug Delivery …, 2024 - Elsevier
Adoptive T cell transfer has shown great success in treating blood cancers, resulting in a
growing number of FDA-approved therapies using chimeric antigen receptor (CAR) …

Microfluidic Approaches for Gene Delivery and Therapy

M Parekh, Z Ali - … Sciences: Formulation, Drug Delivery, Screening, and …, 2024 - Springer
Gene editing techniques such as Clustered Regularly Interspaced Short Palindromic
Repeats (CRISPR/Cas9) have been developed to target a gene into cells, which greatly …

[BOK][B] Programmable Assembly of Genetically Engineered Human Tissues

J Lu - 2024 - search.proquest.com
Genetically engineered cells promise to revolutionize our ability to pattern human tissues.
Genetic approaches to guiding cell differentiation provide rapid and efficient methods to …