Agonists and antagonists of TGF-β family ligands

C Chang - Cold Spring Harbor perspectives in biology, 2016 - cshperspectives.cshlp.org
The discovery of the transforming growth factor β (TGF-β) family ligands and the realization
that their bioactivities need to be tightly controlled temporally and spatially led to intensive …

Deep sequencing reveals unique small RNA repertoire that is regulated during head regeneration in Hydra magnipapillata

S Krishna, A Nair, S Cheedipudi, D Poduval… - Nucleic acids …, 2013 - academic.oup.com
Small non-coding RNAs such as miRNAs, piRNAs and endo-siRNAs fine-tune gene
expression through post-transcriptional regulation, modulating important processes in …

Molecular signature of an ancient organizer regulated by Wnt/β-catenin signalling during primary body axis patterning in Hydra

PC Reddy, A Gungi, S Ubhe, SJ Pradhan… - Communications …, 2019 - nature.com
Wnt/β-catenin signalling has been shown to play a critical role during head organizer
formation in Hydra. Here, we characterized the Wnt signalling regulatory network involved in …

[PDF][PDF] Cell signaling molecules in hydra: insights into evolutionarily ancient functions of signaling pathways

S Ghaskadbi - Int. J. Dev. Biol, 2020 - academia.edu
Hydra, a Cnidarian believed to have been evolved about 60 million years ago, has been a
favorite model for developmental biologists since Abraham Trembley introduced it in 1744 …

Generic and context-dependent gene modulations during Hydra whole body regeneration

Y Wenger, W Buzgariu, C Perruchoud, G Loichot… - BioRxiv, 2019 - biorxiv.org
The cnidarian Hydra is a classical model of whole-body regeneration. Historically, Hydra
apical regeneration has received more attention than its basal counterpart, most studies …

Loss of noggin1, a classic embryonic inducer gene, in elasmobranchs

GV Ermakova, IV Meyntser, AG Zaraisky… - Scientific Reports, 2024 - nature.com
Secreted proteins of the Noggin family serve as pivotal regulators of early development and
cell differentiation in all multicellular animals, including vertebrates. Noggin1 was identified …

[PDF][PDF] Identification and characterization of VEGF and FGF from Hydra

LS Krishnapati, S Ghaskadbi - Int J Dev Biol, 2013 - researchgate.net
Identification and characterization of VEGF and FGF from Hydra Page 1 Identification and
characterization of VEGF and FGF from Hydra LAKSHMI-SUREKHA KRISHNAPATI and …

The Molecular Mechanism of Body Axis Induction in Lampreys May Differ from That in Amphibians

GV Ermakova, AV Kucheryavyy, AG Zaraisky… - International Journal of …, 2024 - mdpi.com
Lamprey homologues of the classic embryonic inducer Noggin are similar in expression
pattern and functional properties to Noggin homologues of jawed vertebrates. All noggin …

[PDF][PDF] Invertebrate alternatives for toxicity testing: hydra stakes its claim

V Patwardhan, S Ghaskadbi - Altex Proc, 2013 - proceedings.altex.org
The use of vertebrate models in toxicity testing is often challenged for scientiic, ethical, and
philosophic reasons. Hydra, a freshwater cnidarian, may prove to be useful in this regard. Its …

[PDF][PDF] Non-developmental dimensions of adult regeneration in Hydra

B Galliot, W Buzgariu, Q Schenkelaars… - International Journal of …, 2018 - researchgate.net
An essential dimension of 3D regeneration in adult animals is developmental, with the
formation of organizers from somatic tissues. These organizers produce signals that recruit …