Method and system for treating cancer cachexia

KR Kovarik, JE Kovarik - US Patent 9,730,967, 2017 - Google Patents
Related US Application Data (63) Continuation-in-part of application No. 15/228, 454, filed
on Aug. 4, 2016, now Pat. No. 9, 585, 920, which is a continuation-in-part of application No …

Methods of using antigen binding proteins to proprotein convertase subtilisin kexin type 9 (PCSK9)

SM Jackson, NPC Walker, DE Piper, B Shan… - US Patent …, 2015 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
39951467&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Enhancing antibody patent protection using epitope map** information

X Deng, U Storz, BJ Doranz - MAbs, 2018 - Taylor & Francis
As the $100 B therapeutic monoclonal antibody (mAb) market continues to grow, developers
of therapeutic mAbs increasingly face the need to strengthen patent protection of their …

Anti-PCSK9 antibodies and use thereof

AL Feldhaus, LF Garcia-Martinez, BH Dutzar… - US Patent …, 2016 - Google Patents
2013-05-07 Assigned to ALDER BIOPHARMACEUTICALS, INC. reassignment ALDER
BIOPHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE …

Methods for reducing remnant cholesterol and other lipoprotein fractions by administering an inhibitor of proprotein convertase subtilisin kexin-9 (PCSK9)

G Swergold, WJ Sasiela, RC Pordy - US Patent 10,111,953, 2018 - Google Patents
The present invention provides methods for reducing various lipoprotein fractions in the
serum of patients. The methods of the invention include reducing serum remnant …

Monoclonal antibodies to proprotein convertase subtilisin kexin type 9 (PCSK9)

SM Jackson, NPC Walker, DE Piper, B Shan… - US Patent …, 2018 - Google Patents
Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9
(PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by …

Method and system for treating cancer and other age-related diseases by extending the healthspan of a human

KR Kovarik, JE Kovarik - US Patent 10,314,865, 2019 - Google Patents
Various embodiments of the present invention are directed to the field of Oncology, and in
particular, embodiments directed to a method of ameliorating, treating, or preventing a …

PCSK9 antagonists

H Liang, YN Abdiche, JFC Riggers, BC Gomes… - US Patent …, 2015 - Google Patents
The present invention provides antagonizing antibodies, anti gen-binding portions thereof,
and aptamers that bind to pro protein convertase subtilisin kexin type 9 (PCSK9). Also …

Method and system for treating cancer and other age-related diseases by extending the healthspan of a human

KR Kovarik, JE Kovarik - US Patent 10,716,815, 2020 - Google Patents
Various embodiments of the present invention are directed to the field of Oncology, and in
particular, embodiments directed to a method of ameliorating, treating, or preventing a …

Precision medicine by targeting PD-L1 variants for treatment of cancer

JR Clube - US Patent 9,045,545, 2015 - Google Patents
US9045545B1 - Precision medicine by targeting PD-L1 variants for treatment of cancer - Google
Patents US9045545B1 - Precision medicine by targeting PD-L1 variants for treatment of cancer …