For the longest time, the field of nucleic acid delivery has remained skeptical whether or not
polycationic drug carrier systems would ever make it into clinical practice. Yet, with the …

Micelleplexes show great promise as effective polymeric delivery systems for nucleic acids.
Although studies have shown that spherical micelleplexes can exhibit superior cellular …

As nucleic acid (NA) technologies continue to revolutionize medicine, new delivery vehicles
are needed to effectively transport NA cargoes into cells. Uniform and length-tunable …

Research on the improvement and fabrication of polymeric systems as non-viral gene
delivery carriers is required for their implementation in gene therapy. Random copolymers …

Here, we demonstrate that the spatial distribution of lipophilic cations governs the
complexation pathways, serum stability, and biological performance of polymer–pDNA …

Lipid-polymer chimeric (hybrid) nanosystems are promising platforms for the design of
effective gene delivery vectors. In this regard, we developed DNA nanocarriers comprised of …

Natural polysaccharides can serve as carriers of genes owing to their intrinsic
biocompatibility, biodegradability, and low toxicity. Additionally, they can be easily …

Polylactic acid (PLA) is one of promising biocompatible and biodegradable polyester. Poly
(2-hydroxyethyl methacrylate)(PHEMA) is a polymer with good hydrophilicity. The …

Lipid-polymer chimeric (hybrid) nanosystems are promising platforms for the design of
effective gene delivery vectors. In this regard, we developed DNA nanocarriers comprised of …

Lipid-polymer chimeric (hybrid) nanosystems are promising platforms for the design of
effective gene delivery vectors. In this regard, we developed DNA nanocarriers comprised of …