[HTML][HTML] Th17 cells and the IL-23/IL-17 axis in the pathogenesis of periodontitis and immune-mediated inflammatory diseases

K Bunte, T Beikler - International journal of molecular sciences, 2019 - mdpi.com
Innate immunity represents the semi-specific first line of defense and provides the initial host
response to tissue injury, trauma, and pathogens. Innate immunity activates the adaptive …

Roles of Porphyromonas gingivalis and its virulence factors in periodontitis

W Xu, W Zhou, H Wang, S Liang - Advances in protein chemistry and …, 2020 - Elsevier
Periodontitis is an infection-driven inflammatory disease, which is characterized by gingival
inflammation and bone loss. Periodontitis is associated with various systemic diseases …

Oral mucosal epithelial cells

S Groeger, J Meyle - Frontiers in immunology, 2019 - frontiersin.org
Cellular Phenotype and Apoptosis: The function of epithelial tissues is the protection of the
organism from chemical, microbial, and physical challenges which is indispensable for …

Maintaining homeostatic control of periodontal bone tissue

JD Hathaway‐Schrader, CM Novince - Periodontology 2000, 2021 - Wiley Online Library
Alveolar bone is a unique osseous tissue due to the proximity of dental plaque biofilms.
Periodontal health and homeostasis are mediated by a balanced host immune response to …

Basic biology and role of interleukin‐17 in immunity and inflammation

C Zenobia, G Hajishengallis - Periodontology 2000, 2015 - Wiley Online Library
Interleukin‐17 (also known as interleukin‐17A) is a key cytokine that links T‐cell activation to
neutrophil mobilization and activation. As such, interleukin‐17 can mediate protective innate …

The periodontal war: microbes and immunity

JL Ebersole, D Dawson III, P Emecen‐Huja… - Periodontology …, 2017 - Wiley Online Library
Maintenance of periodontal health or transition to a periodontal lesion reflects the
continuous and ongoing battle between the vast microbial ecology in the oral cavity and the …

Comorbidity of periodontal disease: two sides of the same coin? An introduction for the clinician

P Holmstrup, C Damgaard, I Olsen… - Journal of oral …, 2017 - Taylor & Francis
Increasing evidence has suggested an independent association between periodontitis and
a range of comorbidities, for example cardiovascular disease, type 2 diabetes, rheumatoid …

Th17 cells in periodontitis and its regulation by A20

N Huang, H Dong, Y Luo, B Shao - Frontiers in immunology, 2021 - frontiersin.org
Periodontitis is a prevalent chronic disease that results in loss of periodontal ligament and
bone resorption. Triggered by pathogens and prolonged inflammation, periodontitis is …

Association between Porphyromonas Gingivalis and systemic diseases: Focus on T cells-mediated adaptive immunity

C Li, R Yu, Y Ding - Frontiers in cellular and infection microbiology, 2022 - frontiersin.org
The association between periodontal disease and systemic disease has become a research
hotspot. Porphyromonas gingivalis (P. gingivalis), a crucial periodontal pathogen, affects the …

The presence, function and regulation of IL‐17 and Th17 cells in periodontitis

WC Cheng, FJ Hughes… - Journal of clinical …, 2014 - Wiley Online Library
Periodontitis (PD) is a chronic inflammatory disease characterised by tissue inflammation
and destruction of the associated alveolar bone. It is caused by the colonisation of the …