Dendritic cell subsets and locations
S Balan, M Saxena, N Bhardwaj - International review of cell and molecular …, 2019 - Elsevier
Dendritic cells (DCs) are a unique class of immune cells that act as a bridge between innate
and adaptive immunity. The discovery of DCs by Cohen and Steinman in 1973 laid the …
and adaptive immunity. The discovery of DCs by Cohen and Steinman in 1973 laid the …
Thymic epithelial cell heterogeneity: TEC by TEC
N Kadouri, S Nevo, Y Goldfarb… - Nature Reviews …, 2020 - nature.com
The generation of a functional T cell repertoire in the thymus is mainly orchestrated by
thymic epithelial cells (TECs), which provide develo** T cells with cues for their …
thymic epithelial cells (TECs), which provide develo** T cells with cues for their …
CD83: activation marker for antigen presenting cells and its therapeutic potential
CD83 is a member of the immunoglobulin (Ig) superfamily and is expressed in membrane
bound or soluble forms. Membrane CD83 (mCD83) can be detected on a variety of activated …
bound or soluble forms. Membrane CD83 (mCD83) can be detected on a variety of activated …
The CD83 molecule–an important immune checkpoint
L Grosche, I Knippertz, C König, D Royzman… - Frontiers in …, 2020 - frontiersin.org
The CD83 molecule has been identified to be expressed on numerous activated immune
cells, including B and T lymphocytes, monocytes, dendritic cells, microglia, and neutrophils …
cells, including B and T lymphocytes, monocytes, dendritic cells, microglia, and neutrophils …
Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells
S Žuklys, A Handel, S Zhanybekova, F Govani… - Nature …, 2016 - nature.com
Thymic epithelial cell differentiation, growth and function depend on the expression of the
transcription factor Foxn1; however, its target genes have never been physically identified …
transcription factor Foxn1; however, its target genes have never been physically identified …
Manipulating dendritic cell biology for the active immunotherapy of cancer
DW O'Neill, S Adams, N Bhardwaj - Blood, 2004 - ashpublications.org
Dendritic cells (DCs) are specialized antigen-presenting cells (APCs) that have an
unequaled capacity to initiate primary immune responses, including tolerogenic responses …
unequaled capacity to initiate primary immune responses, including tolerogenic responses …
Critical roles for transcription factor GATA-3 in thymocyte development
SY Pai, ML Truitt, CN Ting, JM Leiden, LH Glimcher… - Immunity, 2003 - cell.com
The transcription factor GATA-3 is expressed at every stage of thymic development, but its
role in thymocyte differentiation is unknown. The fact that RAG chimeric animals lacking …
role in thymocyte differentiation is unknown. The fact that RAG chimeric animals lacking …
The genetic prehistory of the Andean highlands 7000 years BP though European contact
The peopling of the Andean highlands above 2500 m in elevation was a complex process
that included cultural, biological, and genetic adaptations. Here, we present a time series of …
that included cultural, biological, and genetic adaptations. Here, we present a time series of …
CD83 on dendritic cells: more than just a marker for maturation
CD83 has been known for a long time to be one of the best markers for mature dendritic
cells (DCs). Studies with herpes simplex virus type 1 (HSV-1)-infected DCs, whereby the …
cells (DCs). Studies with herpes simplex virus type 1 (HSV-1)-infected DCs, whereby the …
CD83 expression on dendritic cells and T cells: correlation with effective immune responses
C Aerts‐Toegaert, C Heirman… - European journal of …, 2007 - Wiley Online Library
Human CD83 is a marker molecule for mature dendritic cells (DC) and is also expressed on
activated B and T cells. Although CD83 has been implicated in immune responses, its …
activated B and T cells. Although CD83 has been implicated in immune responses, its …