Nanoparticle-mediated targeted drug delivery for breast cancer treatment
Breast cancer (BC) is the most common malignancy in women worldwide, and one of the
deadliest after lung cancer. Currently, standard methods for cancer therapy including BC are …
deadliest after lung cancer. Currently, standard methods for cancer therapy including BC are …
Regulation of progesterone receptor expression in endometriosis, endometrial cancer, and breast cancer by estrogen, polymorphisms, transcription factors, epigenetic …
H Pu, X Wen, DX Luo, Z Guo - The Journal of Steroid Biochemistry and …, 2023 - Elsevier
The uterus and breasts are hormone-responsive tissues. Progesterone and estradiol
regulate gonadotropin secretion, prepare the endometrium for implantation, maintain …
regulate gonadotropin secretion, prepare the endometrium for implantation, maintain …
Di (2-ethylhexyl) phthalate (DEHP) increases proliferation of epithelial breast cancer cells through progesterone receptor dysregulation
B Crobeddu, E Ferraris, E Kolasa, I Plante - Environmental research, 2019 - Elsevier
Abstract The di (2-ethylhexyl) phthalate (DEHP) is a plasticizer incorporated to plastic
matrices of widely used consumer products. However, it is gradually released from these …
matrices of widely used consumer products. However, it is gradually released from these …
Aptamer-based sensing of breast cancer biomarkers: a comprehensive review of analytical figures of merit
Introduction Accurate determination of the aberrantly expressed biomarkers such as human
epidermal growth factor receptor 2 (HER2), carcinoembryonic antigen (CEA), platelet …
epidermal growth factor receptor 2 (HER2), carcinoembryonic antigen (CEA), platelet …
Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk
Tissue stem-progenitor cell frequency has been implicated in tumor risk and progression,
but tissue-specific factors linking these associations remain ill-defined. We observed that stiff …
but tissue-specific factors linking these associations remain ill-defined. We observed that stiff …
Mammary gland: From embryogenesis to adult life
G Musumeci, P Castrogiovanni, MA Szychlinska… - Acta histochemica, 2015 - Elsevier
The aim of this review is to focus on the molecular factors that ensure the optimal
development and maintenance of the mammary gland thanks to their integration and …
development and maintenance of the mammary gland thanks to their integration and …
Biological and clinical impact of imbalanced progesterone receptor isoform ratios in breast cancer
CA Lamb, VT Fabris, BM Jacobsen… - Endocrine-related …, 2018 - erc.bioscientifica.com
There is a consensus that progestins and thus their cognate receptor molecules, the
progesterone receptors (PRs), are essential in the development of the adult mammary gland …
progesterone receptors (PRs), are essential in the development of the adult mammary gland …
Co-adjuvant therapy efficacy of catechin and procyanidin B2 with docetaxel on hormone-related cancers in vitro
MJ Núñez-Iglesias, S Novio, C García… - International Journal of …, 2021 - mdpi.com
Prostate (PC) and breast cancer (BC) are heterogeneous hormonal cancers. Treatment
resistance and adverse effects are the main limitations of conventional chemotherapy …
resistance and adverse effects are the main limitations of conventional chemotherapy …
EpiBrCan-Lite: A lightweight deep learning model for breast cancer subtype classification using epigenomic data
Background and objectives Early breast cancer subtypes classification improves the survival
rate as it facilitates prognosis of the patient. In literature this problem was prominently solved …
rate as it facilitates prognosis of the patient. In literature this problem was prominently solved …
Bringing androgens up a NOTCH in breast cancer
While it has been known for decades that androgen hormones influence normal breast
development and breast carcinogenesis, the underlying mechanisms have only been …
development and breast carcinogenesis, the underlying mechanisms have only been …