Nanoparticle-mediated targeted drug delivery for breast cancer treatment

PY Liyanage, SD Hettiarachchi, Y Zhou, A Ouhtit… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Breast cancer (BC) is the most common malignancy in women worldwide, and one of the
deadliest after lung cancer. Currently, standard methods for cancer therapy including BC are …

Regulation of progesterone receptor expression in endometriosis, endometrial cancer, and breast cancer by estrogen, polymorphisms, transcription factors, epigenetic …

H Pu, X Wen, DX Luo, Z Guo - The Journal of Steroid Biochemistry and …, 2023 - Elsevier
The uterus and breasts are hormone-responsive tissues. Progesterone and estradiol
regulate gonadotropin secretion, prepare the endometrium for implantation, maintain …

Di (2-ethylhexyl) phthalate (DEHP) increases proliferation of epithelial breast cancer cells through progesterone receptor dysregulation

B Crobeddu, E Ferraris, E Kolasa, I Plante - Environmental research, 2019 - Elsevier
Abstract The di (2-ethylhexyl) phthalate (DEHP) is a plasticizer incorporated to plastic
matrices of widely used consumer products. However, it is gradually released from these …

Aptamer-based sensing of breast cancer biomarkers: a comprehensive review of analytical figures of merit

R Ahirwar, N Khan, S Kumar - Expert Review of Molecular …, 2021 - Taylor & Francis
Introduction Accurate determination of the aberrantly expressed biomarkers such as human
epidermal growth factor receptor 2 (HER2), carcinoembryonic antigen (CEA), platelet …

Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk

JJ Northey, MK Hayward, Y Yui, C Stashko, FB Kai… - Cell Stem Cell, 2024 - cell.com
Tissue stem-progenitor cell frequency has been implicated in tumor risk and progression,
but tissue-specific factors linking these associations remain ill-defined. We observed that stiff …

Mammary gland: From embryogenesis to adult life

G Musumeci, P Castrogiovanni, MA Szychlinska… - Acta histochemica, 2015 - Elsevier
The aim of this review is to focus on the molecular factors that ensure the optimal
development and maintenance of the mammary gland thanks to their integration and …

Biological and clinical impact of imbalanced progesterone receptor isoform ratios in breast cancer

CA Lamb, VT Fabris, BM Jacobsen… - Endocrine-related …, 2018 - erc.bioscientifica.com
There is a consensus that progestins and thus their cognate receptor molecules, the
progesterone receptors (PRs), are essential in the development of the adult mammary gland …

Co-adjuvant therapy efficacy of catechin and procyanidin B2 with docetaxel on hormone-related cancers in vitro

MJ Núñez-Iglesias, S Novio, C García… - International Journal of …, 2021 - mdpi.com
Prostate (PC) and breast cancer (BC) are heterogeneous hormonal cancers. Treatment
resistance and adverse effects are the main limitations of conventional chemotherapy …

EpiBrCan-Lite: A lightweight deep learning model for breast cancer subtype classification using epigenomic data

P Bedi, S Rani, B Gupta, V Bhasin, P Gole - Computer Methods and …, 2025 - Elsevier
Background and objectives Early breast cancer subtypes classification improves the survival
rate as it facilitates prognosis of the patient. In literature this problem was prominently solved …

Bringing androgens up a NOTCH in breast cancer

GA Tarulli, LM Butler, WD Tilley… - Endocrine-related …, 2014 - erc.bioscientifica.com
While it has been known for decades that androgen hormones influence normal breast
development and breast carcinogenesis, the underlying mechanisms have only been …