Nucleobase modifications are prevalent in eukaryotic mRNA and their discovery has
resulted in the emergence of epitranscriptomics as a research field. The most abundant …

Abstract N 6-Methyladenosine (m6A) is one of the most abundant modifications of the
epitranscriptome and is found in cellular RNAs across all kingdoms of life. Advances in …

Over decades, researchers have focused on the epigenetic control of DNA-templated
processes. Histone modification, DNA methylation, chromatin remodeling, RNA modification …

Over the past decade, mRNA modifications have emerged as important regulators of gene
expression control in cells. Fueled in large part by the development of tools for detecting …

RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

Following its transcription, RNA can be modified by> 170 chemically distinct types of
modifications—the epitranscriptome. In recent years, there have been substantial efforts to …

Specific chemical modifications of biological molecules are an efficient way of regulating
molecular function, and a plethora of downstream signalling pathways are influenced by the …

Hepatocellular carcinoma (HCC) accounts for the majority of primary liver cancers and is
characterized by high recurrence and heterogeneity, yet its mechanism is not well …

Since the identification of the first RNA demethylase and the establishment of methylated
RNA immunoprecipitation-sequencing methodology 6 to 7 years ago, RNA methylation has …

Abstract N 6-methyladenosine (m6A) is a chemical modification present in multiple RNA
species, being most abundant in mRNAs. Studies on enzymes or factors that catalyze …